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Allergy to a Carbon-Functional Organic Silicon Compound, Dimethyldi-(4-hydroxyphenyl)-silane

Abstract

THE noxious effects of certain inorganic silicon compounds are well known1. Polymeric organic silicon compounds, on the contrary, are chemically very inert and show a low toxicity2. Some organic silicon compounds may, however, produce toxic effects3.

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References

  1. Holt, P. F., Pneumoconiosis (Edward Arnold, Publishers, Ltd., London, 1957).

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  2. McGregor, R. R., Silicones in Medicine and Surgery (distributed by Dow Corning Corporation, 1957).

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  3. Eaborn, C., Organosilicon Compounds, 473 (Butterworths Scientific Publications, London, 1960).

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  4. Rochow, E. G., An Introduction to the Chemistry of the Silicones, 1 (John Wiley and Sons, Inc., New York, 1951).

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  5. Speier, J. L., J. Amer. Chem. Soc., 74, 1003 (1952). Speier, Dow Corning Corporation, Midland, Michigan, who synthesized dimethyldi-(4-hydroxyphenyl)-silane, kindly supplied a sample.

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  6. Fregert, S., and Rorsman, H., Acta Dermat.-Venereol., 40, 206 (1960).

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FREGERT, S., RORSMAN, H. Allergy to a Carbon-Functional Organic Silicon Compound, Dimethyldi-(4-hydroxyphenyl)-silane. Nature 192, 989–990 (1961). https://doi.org/10.1038/192989b0

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