Abstract
As part of a programme involving the investigation of general laboratory methods for the preparation of fluoropyridines1, we wish to report the synthesis of 2,6-difluoropyridine. The only other recorded example of a pyridine containing more than one nuclear fluorine is pentafluoropyridine2,3, which was prepared by methods best suited for the synthesis of perfluoro-aromatic compounds.
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Finger, G. C., and Starr, L. D., J. Amer. Chem. Soc., 81, 2674 (1959).
Stacey, P. M., and Tatlow, J. C., Nature, 186, 231 (1960).
Haszeldine, R. N., et al., Proc. Chem. Soc., 211 (1960).
Roe, A., Cheek, P. H., and Hawkins, G. F., J. Amer. Chem. Soc., 71, 4152 (1949).
Miller, W. K., Knight, S. B., and Roe, A., J. Amer. Chem. Soc., 72, 4765 (1950).
Roe, A., and Hawkins, G. F., J. Amer. Chem. Soc., 69, 2443 (1947).
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FINGER, G., STARR, L. 2,6-Difluoropyridine. Nature 191, 595 (1961). https://doi.org/10.1038/191595a0
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DOI: https://doi.org/10.1038/191595a0
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