Letter | Published:

Pharmacology of the Alkaloidal Fraction from the Bark of the Jamaican Shade Tree Pithecolobium samath Benth.

Naturevolume 191page287 (1961) | Download Citation



A PHARMACOLOGICAL screening programme of extracts of plants used as folk medicines in Jamaica for the preparation of the so-called ‘bush teas’ is being carried out in collaboration with a group under Prof. L. J. Haynes at the Department of Chemistry, and with Dr. P. C. Feng at the Department of Physiology, University College of the West Indies, Jamaica. The shade tree, Pithecolobium samath Benth., was selected for detailed study. The main alkaloid from its bark, pithecolobine, had already been isolated by Wiesner et al.1, who have given its partial structure2.

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    Wiesner, K., MacDonald, D. M., Valenta, Z., and Armstrong, R., Canad. J. Chem., 30, 761 (1952).

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    Wiesner, K., and Orr, D. E., Tetrahedron Letters, 16, 11 (1960).

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    Munier, R., and Machboeuf, M., Bull. Soc. Chim. Biol., 31, 1144 (1949).

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  1. Department of Medical Biochemistry and Pharmacology, University of Birmingham

    • B. E. LEONARD
    •  & H. S. A. SHERRATT


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