A Seasonal Rhythm in the Presentation of Bone Sarcoma in Man

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FROM a study of the ætiology of osteogenic sarcoma in man carried out during the past four years, it has been possible to demonstrate certain trends in the age and sex incidence of these relatively rare neoplasms1,2. Probably the most interesting features are the observations that the tumours tend to arise at an earlier age in females among adolescents, and also the higher incidence of tumours of the arm and pectoral girdle at an earlier age compared with those of the leg and pelvis in juveniles of both sexes. On comparison of the mean ages of groups of osteogenic sarcomata in adolescent males and females, whether for the whole skeleton or for individual bones, the differences of mean ages (male minus female) are seldom statistically significant, nevertheless they are almost invariably in the same direction.

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  1. 1

    Price, C. H. G., Brit. J. Cancer, 9, 558 (1955).

  2. 2

    Price, C. H. G., J. Bone and Joint Surg., 40, B, 574 (1958).

  3. 3

    Brody, S., “Bioenergetics and Growth” (Reinhold Pub. Corp., New York, 1945).

  4. 4

    Tanner, J. M., “Growth at Adolescence” (Blackwell Scientific Pub., Oxford, 1955).

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PRICE, C. A Seasonal Rhythm in the Presentation of Bone Sarcoma in Man. Nature 184, BA76–BA77 (1959) doi:10.1038/184076a0b

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