New Antiadrenergic Compounds

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WE have found that the benzyl quaternary ammonium compounds (I, patents pending) have a novel and highly specific blocking action on the peripheral sympathetic nervous system, which resembles that following section of adrenergic nerves and differs from that produced by adrenolytics, ganglion-blocking agents and reserpine.

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  1. 1

    Hey, P., and Willey, G. L., Brit. J. Pharmacol., 9, 471 (1954).

  2. 2

    Coupland, R. E., and Exley, K. A., Brit. J. Pharmacol., 12, 306 (1957).

  3. 3

    Bain, W. A., and Fielden, R., Lancet, ii, 472 (1957).

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BOURA, A., COPP, F. & GREEN, A. New Antiadrenergic Compounds. Nature 184, BA70–BA71 (1959) doi:10.1038/184070a0b

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