Abstract
FOLLICLE material referred to as wool roots can be prepared in quantity from fresh sheep-skin by Ellis's method1. Each wool root consists of a bulb region, a pre-keratinization region and some fully keratinized fibre. Frequently, the inner root sheath is found to be attached to the wool root. Previous studies of homogenates of wool roots revealed the presence of several enzymes2,3, some of which have been localized in hair follicles by histochemical methods4,5. Very little investigation of enzymes concerned with protein metabolism in the hair follicle has been made, despite the fact that protein synthesis is the major activity of this tissue.
Similar content being viewed by others
Article PDF
References
Ellis, W. J., Nature, 162, 957 (1948).
Ellis, W. J., Gillespie, J. M., and Lindley, H., Nature, 165, 545 (1950).
Gillespie, J. M., Aust. J. Biol. Sci., 9, 448 (1956).
Rogers, G. E., Quart. J. Micro. Sci., 94, 253 (1953).
Montagna, W., “Structure and Function of Skin” (Academic Press, New York, 1956).
Hanes, C. S., Hird, F. J. R., and Isherwood, F. A., Biochem. J., 51, 25 (1952).
Hird, F. J. R., and Springell, P. H., Biochem. J., 56, 417 (1954).
Rogers, G. E. (unpublished experiments).
Rogers, G. E., Biochim. Biophys. Acta, 29, 33 (1958).
Szörenyi, E., Elödi, P., and Deutsch, T., Acta Physiol. Acad. Sci. Hung., 5, 337 (1954).
Rogers, G. E., and Simmonds, D. H., Nature, 182, 186 (1958).
Haurowitz, F., et al., J. Biol. Chem., 224, 827 (1957).
Binkley, F., Exp. Cell Res., Supp. 2, 145 (Academic Press, New York, 1952).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ROGERS, G., SPRINGELL, P. Amino-Acid Metabolism in Wool Roots. Nature 183, 993 (1959). https://doi.org/10.1038/183993a0
Issue Date:
DOI: https://doi.org/10.1038/183993a0
This article is cited by
-
Epidermal and hair follicle trans glutaminases and crosslinking in skin
Molecular and Cellular Biochemistry (1984)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.