Abstract
MILK and liver xanthine oxidase are inhibited by sodium salicylate in vitro 1. Bergel et al. 2 were able to utilize this property for the stabilization of xanthine oxidase by adding salicylate to the process of purification of the enzyme.
Similar content being viewed by others
Article PDF
References
Lutwak-Mann, C., Biochem. J., 36, 706 (1942).
Bergel, F., and Bray, R. C., Nature, 178, 88 (1956).
Affonso, O. R., Mitidieri, E., Ribeiro, L. P., and Villela, G. G., Proc. Soc. Exp. Biol. Med., 90, 527 (1955).
Drill, V. A., “Pharmacology in Medicine” (McGraw-Hill Book Co., Inc., 1958).
Bruns, F., and Neuhaus, J., Arch. Biochem. Biophys., 55, 588 (1955).
Villela, G. G., Mitidieri, E., and Affonso, O. R., Nature, 175, 1087 (1956).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
MITIDIERI, E., AFFONSO, O. Effect of Salicylate on Blood and Liver Xanthine Dehydrogenase of Rats. Nature 183, 471 (1959). https://doi.org/10.1038/183471a0
Issue Date:
DOI: https://doi.org/10.1038/183471a0
This article is cited by
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.