Abstract
ACQUIRED immunological tolerance of heterologous cells is of much lower degree than tolerance of homologous cells1. In experimental embryonal parabiosis2, a large quantity of powerful antigenic stimulus is administered; this acts for a relatively long time during the ‘adaptive period’ and usually results in the formation of cell chimeras. A relatively high degree of heterologous tolerance was sometimes obtained by this method, for a prolonged survival of heterografts has been found in turkey–chicken parabionts1, and an interspecific blood chimera demonstrated3.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Hašek, M., Cs. biologie, 3, 327 (1954).
Hašek, M., Cs. biologie, 2, 25 (1953).
Hraba, T., Folia Biologica, Prague, 2, 165 (1956).
Ottesen, J., Nature, 162, 730 (1948). Brace, K. C., and Altland, P. D., Proc. Soc. Exp. Biol. and Med., 92, 615 (1956). Rodnan, G. P., Ebough, jun., F. G., and Fox, M. R. S., Blood, 12, 355 (1957).
Mitchison, N. A., Cs. biologie, 7, 253 (1958). Sinionsen, M., ibid., 7, 269 (1955). Hort, J., and Hraba, T., ibid., 7, 283 (1958).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
HAŠEK, M., HRABA, T. & HORT, J. Acquired Immunological Tolerance of Heterografts. Nature 183, 1199–1200 (1959). https://doi.org/10.1038/1831199a0
Issue Date:
DOI: https://doi.org/10.1038/1831199a0
This article is cited by
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
