Abstract
A NUMBER of C21 steroids characterized by the 17: 20-dihydroxy-20-methyl side-chain at C17 have been isolated from the urine of normal people1,2 and from the urine of patients with adrenocortical hyper-plasia3 or adrenocortical tumours4 (see Table 1). The separation and identification of members of this group of steroids is necessary for the study of their normal and abnormal metabolic formation and excretion; the following is a method which is capable of separating, detecting and estimating quantitatively all such urinary steroids so far isolated.
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References
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COX, R. Separation, Detection and Estimation of C21 17: 20-Dihydroxy-20-methyl-steroids. Nature 181, 638–639 (1958). https://doi.org/10.1038/181638b0
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DOI: https://doi.org/10.1038/181638b0
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