Letter | Published:

Isolation of a New Flavin produced by an Actinomycete


SINCE the discovery that riboflavin is produced by Eremothecium ashbyii and Ashbya gossypii 1, a great number of bacteria and fungi have been found capable of producing this and other closely related substances2. Among the Actinomycetales only a few species of Mycobacterium 3 have been reported capable of producing riboflavin, while no true Actinomycete has ever been found to possess such a capacity.

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  1. 1

    Guilliermond, A., Fontaine, M., and Raffy, A., C.R. Acad. Sci., Paris, 201, 1077 (1935).

  2. 2

    Peterson, W. M., and Peterson, M. S., Bact. Rev., 9, 49 (1945). Van Lanen, J. M., and Tanner, F. W., Vitamins and Hormones, 6, 163 (1948). Pridham, T. G., Econ. Bot., 6, 185 (1952).

  3. 3

    Mayer, R. L., and Rodbart, M., Arch. Biochem., 11, 49 (1946). Smith, M. I., and Emmart, E. W., J. Immunol., 61, 259 (1949).

  4. 4

    Crammer, J. L., Nature, 161, 349 (1948).

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