Abstract
So long ago as 1858, Staedeler and Frerichs1 discovered the presence of large amounts of urea in three species of elasmobranch fishes. Many more have been examined since that time, and it is known to-day that many, and probably all marine, elasmobranchs, including the Holocephali, contain 2–2.5 per cent of urea in their blood and tissues. Freshwater species contain only about 1 per cent of urea. The physiological significance of the resulting uræmia has been ably reviewed by Smith2.
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References
Staedeler, G., and Frerichs, F. T., J. prakt. Chem., 73, 48 (1858).
Smith, H. W., Biol. Rev., 11, 49 (1936).
Baldwin, E., Biol. Rev., 8, 74 (1932).
Grisolia, S., in “Methods in Enzymology” (New York), 2, 350 (1955).
Ratner, S., in “Methods in Enzymology” (New York), 2, 356 (1955).
Archibald, R. M., J. Biol. Chem., 157, 507 (1945).
Jones, M. E., Spector, L., and Lipmann, F., J. Amer. Chem. Soc., 77, 819 (1955).
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BALDWIN, E. Ureogenesis in Elasmobranchs. Nature 181, 1591–1592 (1958). https://doi.org/10.1038/1811591a0
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DOI: https://doi.org/10.1038/1811591a0
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