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Enzymatic Cleavage and Synthesis of L-threo-β-Phenylserine and L-erythro-β-Phenylserine

Abstract

As has been demonstrated in earlier communications, D,L-threo-β-phenylserine-3-14C and D,L-phenylalanine-3-14C are incorporated into the benzoyl moiety of urinary hippuric acid1,2. These results led to the assumption of an enzymatic, in vivo splitting between C2 and C3 of the side-chain, as has been found to occur in vitro for L-phenylserines3,4.

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References

  1. Haberland, G. L., Bruns, F. H., and Altman, K. I., Biochem. Z., 326, 107 (1954).

    PubMed  CAS  Google Scholar 

  2. Bruns, F. H., Haberland, G. L., and Altman, K. I., J. Biol. Chem. (in the press).

  3. Vilenkina, G. I., Doklady Acad. Nauk S.S.S.R., 69, 385 (1949).

    CAS  Google Scholar 

  4. Gilbert, J. B., J. Amer. Chem. Soc., 76, 4183 (1954).

    Article  CAS  Google Scholar 

  5. Shaw, K. N. F., and Fox, S. W., J. Amer. Chem. Soc., 75, 3417, 3421 (1953).

    Article  CAS  Google Scholar 

  6. Karasek, M. A., and Greenberg, D. M., J. Biol. Chem., 227, 191 (1957).

    PubMed  CAS  Google Scholar 

  7. Bruns, F. H., and Fiedler, L., Biochem. Z. (in the press).

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BRUNS, F., FIEDLER, L. Enzymatic Cleavage and Synthesis of L-threo-β-Phenylserine and L-erythro-β-Phenylserine. Nature 181, 1533–1534 (1958). https://doi.org/10.1038/1811533a0

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