Abstract
Bensley and Hoerr1 showed in 1934 that a certain proportion of the cytoplasm of animal cells was insoluble in salt solutions. More recently, Smith and his collaborators2 have shown that as much as 45 per cent of the material which remains after liver cells have been repeatedly extracted with molar salt solutions is lipid; they suggest that this is a complex lipo-protein. Histochemical studies, using sudan colouring agents and the acid hæmatein test for phospholipids, do not seem to indicate the presence of such large amounts of reactive lipids in many cells. These tests do not, however, exclude the possibility that the lipid is present in a ‘masked’ condition, a fact which was recognized by Ciaccio3, who published techniques for detecting lipids when they are combined with other substances.
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References
Bensley, R. R., and Hoerr, N. L., Anat. Rec., 60, 251 (1934).
Smith, J. T., Funckes, A. J., Barak, A. J., and Thomas, L. E., Exp. Cell Res., 13, 96 (1957).
Ciaccio, C., Boll. Soc. Biologia Sper., 1, 47 (1926).
Baker, J. R., Quart. J. Micro. Sci., 85, 1 (1944).
Baker, J. R., Quart. J. Micro. Sci., 90, 293 (1949).
Baker, J. R., Quart. J. Micro. Sci., 87, 441 (1946).
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BRADBURY, S., CLAYTON, BP. Occurrence of ‘Masked Lipid’ in Mouse Pancreas. Nature 181, 1347 (1958). https://doi.org/10.1038/1811347a0
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DOI: https://doi.org/10.1038/1811347a0
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