Abstract
ACTH is prepared mainly from hog pituitaries for medicinal purposes, and Marshall1 showed conclusively that it was localized in the basophil cells of the anterior hypophysis in that animal. So far as we are aware, ACTH has not been extracted previously from human pituitaries, although lyophilized pituitary tissue has been assayed2.
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References
Marshall, J. M., J. Exp. Med., 94, 21 (1951).
Taylor, N. R. W., Loraine, J. A., and Roberts, H. A., J. Endocrin., 9, 334 (1953).
Crooke, A. C., J. Path. Bact., 41, 339 (1935).
Laqueur, G. L., Science, 112, 429 (1950).
Crooke, A. C., and Russell, D. S., J. Path. Bact., 40, 255 (1935).
Currie, A. R., and Symington, T., Ciba Foundation Colloquia on Endocrinology, 9 (1954) (in the press).
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HEWETT, C., CRUICKSHANK, B. & CURRIE, A. Extraction of ACTH from Human Pituitaries. Nature 174, 745–746 (1954). https://doi.org/10.1038/174745a0
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DOI: https://doi.org/10.1038/174745a0
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