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Localization of Erythemal Processes caused by Ultra-Violet Light in Human Skin

Abstract

SINCE the fundamental experiments of Hausser and Vahle1, in 1922, it has been known that two wavelength regions of the ultra-violet spectrum, namely, near 297 mµ and about 250 mµ, have maximum efficiency in producing erythema in human skin. These regions are separated by a region near 280 mµ with small erythemal activity. The explanation for this action spectrum has been sought in the screening function of the superficially situated horny layer which, as a protein with aromatic compounds, has a maximum light absorption2 near 280 mµ

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References

  1. Hausser, K. W., and Vahle, W., Strahlentherapie, 13, 41 (1922). Bachem, A., Strahlentherapie, 39, 30 (1931). Lucas, N. S., Biochem. J., 25, 57 (1931). Miescher, G., Stahlentherapie, 35, 403 (1930). Mitchell, J. S., Proc. Roy. Soc., B, 126, 241 (1939).

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  2. Rottier, P. B., Séméiologie et Thérapeutique, 21, 14 (1951).

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ROTTIER, P., MULLINK, J. Localization of Erythemal Processes caused by Ultra-Violet Light in Human Skin. Nature 170, 574–575 (1952). https://doi.org/10.1038/170574a0

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