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Controversy in multiple myeloma transplants: tandem autotransplants and mini-allografts

Abstract

Autologous stem cell transplantation appears to enhance outcome in multiple myeloma patients. To improve upon these results, various groups have utilized tandem autografts, as well as used reduced-conditioning allogeneic stem cell transplantation. These two approaches, discussed herein, have been promising. Inherent patient selection, however, appears to play a role and much of the data have not yet been subjected to peer-review scrutiny. At present, these strategis remain investigational and cannot be considered the standard-of-care for multiple myeloma patients. Bone Marrow Transplantation (2001) 28, 725–735.

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Vesole, D., Simic, A. & Lazarus, H. Controversy in multiple myeloma transplants: tandem autotransplants and mini-allografts. Bone Marrow Transplant 28, 725–735 (2001). https://doi.org/10.1038/sj.bmt.1703254

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