Abstract
Stokstad and Jukes1 reported that diets supplemented with aureomycin hydro chloride have a growth-stimulating effect. Since then, many reports have confirmed that a number of antibiotics may act as growth stimulants in pigs and poultry. It was of interest to see if nisim2, the antibiotic produced by Str. lactis, had a similar effect. The nisin used was not concentrated or purified, but was obtained by growing the cultures of Str. lactis in skim milk, when 100–200 units/ml. (c. 50 units = 1 µgm.) is always produced.
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References
Stokstad, E. L. R., and Jukes, T. H., Proc. Soc. Exp. Biol. N.Y., 73, 523 (1950).
Mattick, A. T. R., and Hirsch, A., Lancet, ii, 5 (1947).
Hirsch, A., and Grinstead, E., J. Dairy Res., 18, 198 (1951).
Coates, M. E., Harrison, G. F., Kon, S. K., Mann, M. E., and Rose, C. D., Biochem. J., 48, xii (1951).
Braude, R., Kon, S. K., and Mitchell, K. G., Brit. J. Nutrit., 5, viii (1951).
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BARBER, R., BRAUDE, R. & HIRSCH, A. Growth of Pigs given Skim Milk Soured with Nisin-producing Streptococci. Nature 169, 200 (1952). https://doi.org/10.1038/169200a0
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DOI: https://doi.org/10.1038/169200a0
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