Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Light-scattering Studies on Penicillin G Solutions

Nature volume 168, pages 423–424 (1951)Cite this article

Abstract

LITERATURE concerning the physical-chemical state of aqueous systems of penicillin reveals a controversial issue. Claims that micelles, between 200 A. and 5000 A. in length, are formed above a critical concentration of 10,000 units/c.c. (0.6 per cent)1–4 contrast with evidence which indicates that penicillins behave as simple electrolytes5–9. One paper5 reports that colloidal electrolyte behaviour is not reached until 8.26 per cent, a concentration so high as to be of little biological importance.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Hauser, E. A., Kolloid Z., 111, 103 (1948).

    Article  CAS  Google Scholar 

  2. Hauser, E. A., and Marlowe, G. J., J. Phys. Coll. Chem., 54, 1077 (1950).

    Article  CAS  Google Scholar 

  3. Hauser, E. A., Phillips, R. G., and Phillips, J. W., Science, 106, 616 (1947).

    Article  Google Scholar 

  4. Hauser, E. A., Phillips, R. G., Phillips, J. W., and Vavruch, I., J. Phys. Coll. Chem., 53, 287 (1949).

    Article  CAS  Google Scholar 

  5. McBain, J. W., Huff, H., and Brady, A. P., J. Amer. Chem. Soc., 71, 373 (1949).

    Article  CAS  Google Scholar 

  6. Kumer, W. D., and Alpen, E. L., Science, 107, 567 (1948).

    Article  ADS  Google Scholar 

  7. Lund, C. G., and Pedersen-Bjergaard, K., Science, 109, 149 (1949).

    Article  ADS  CAS  Google Scholar 

  8. Klenow, H., Acta Chem. Scandinavia, 1, 328 (1947).

    Article  CAS  Google Scholar 

  9. Woodbury, D. T., and Rosenblum, C., J. Biol. Chem., 171, 447 (1947).

    CAS  PubMed  Google Scholar 

  10. Debye, P., J. Phys. Coll. Chem., 53, 1 (1949).

    Article  CAS  Google Scholar 

  11. Oster, G., Chem. Rev., 43, 319 (1948).

    Article  CAS  Google Scholar 

Download references

Author information

Author notes

  1. C. S. HOCKING: Rotary Foundation Fellow, Adelaide, Australia.

Authors and Affiliations

  1. Baker Laboratory of Chemistry, Cornell University, Ithaca, New York

    C. S. HOCKING

Authors
  1. C. S. HOCKING
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

HOCKING, C. Light-scattering Studies on Penicillin G Solutions. Nature 168, 423–424 (1951). https://doi.org/10.1038/168423a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/168423a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing