Abstract
IT has already been shown1,2 that 4-amino-imidazole-5-carboxamide (I) is a precursor of the purines in E. coli; a purine-requiring mutant of the organism grows in a medium containing this substance. On the other hand, it has been observed3,4 that synthetic 4-amino-imidazole-5-carboxamide is little utilized by a growing culture of E. coli. The following observations will eliminate this apparent discrepancy.
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BEN-ISHAI, R., BERGMANN, E. & VOLCANI, B. Ribosidation of 4-Amino-imidazole-5-carboxamide by Escherichia coli. Nature 168, 1124 (1951). https://doi.org/10.1038/1681124a0
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DOI: https://doi.org/10.1038/1681124a0
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