Abstract
IT is well known that in the mechanism of extra-renal azotæmia the causative factor is the loss of sodium and subsequent dehydration1. According to Gömöri and co-workers2, the causes of dehydration-azotæmia are as follows : (1) blood pressure falls, and in consequence of the dehydration the colloidoncotic pressure of the blood plasma increases, thus resulting in a drop of the glomerular filtration-rate ; (2) circulation is slowing down, contributing thus to the diminished filtration-rate ; (3) excessive rotein catabolism helps to aggravate the uræmic condition.
Similar content being viewed by others
Article PDF
References
Kerpel-Fronius, Ed., Erg. Inn. Med., 51, 624 ( 1936).
Gömöri, P., and co-workers, Acta med. Scand., 92, 347, 515 ( 1937); 102, 591 ( 1939); Z. ges. exp. Med., 104, 22 ( 1938).
Darrow, D. C., and Yannet, H., Amer. J. Dis. Child., 46, 253 ( 1933).
Gömöri, P., and Romhányi, G., Orvosi Hetilap, 89, 21, 336 ( 1948) (in Hungarian).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
GÖMÖRI, P., BÁLINT, P. & HÁRSING, L. Tubular Factors in the Development of Extra-renal Azotæmia. Nature 163, 364 (1949). https://doi.org/10.1038/163364a0
Issue Date:
DOI: https://doi.org/10.1038/163364a0
This article is cited by
-
Zur Bewertung der Inulinclearance
Pfl�gers Archiv f�r die Gesamte Physiologie des Menschen und der Tiere (1960)
-
Tubular Factors in the Development of Extra-renal Azotæmia
Nature (1949)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.