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Relations between the Source of Nitrogen and Antibiotic Formation by Aspergillus Fumigatus, Fresenius

Abstract

MANY papers have been published on the antegoniam of certain micro-organisms against acid-fast bacteria, particularly M. tuberculosis1–13. In this connexion the metabolic products of the various strains of the group Aspergillus are receiving considerable attention. Fumigatin14, spinulosin15, helvolic acid16 and gliotoxin17 are the four metabolic products of A. fumigatus which show considerable antibiotic activity. The present communication relates to a study of the formation of antibiotic activity and the source of nitrogen by A. fumigatus, Fresenius, The strain of this organism was obtained from the Imperial Institute of Agricultural Research, New Delhi, isolated by Mr. G. Smith of the London School of Tropical Medicine.

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RAO, R., VENKATARAMAN, P. Relations between the Source of Nitrogen and Antibiotic Formation by Aspergillus Fumigatus, Fresenius. Nature 158, 241–242 (1946). https://doi.org/10.1038/158241a0

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