Abstract
A NOTEWORTHY feature of the published synthetic work relevant to the chemotherapy of malaria is the extent to which attention has been concentrated on the preparation of active agents derived from either quinoline or acridine, of which the two outstanding examples are respectively, pamaquin and mepacrine. By comparison, little information is available concerning the effectiveness of other structural types, with the important exception of paludrine, the discovery of which was announced recently1.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Nature, 156, 596 (1945).
J. Gen. Chem. U.S.S.R., 8, 1797 (1938). Chem. Abs., 33, 4993 (1939).
Schönhofer, Z. physiol. Chem., 274, 1 (1942).
Eng. Pat. Appl. 27673/38.
Ann. Trap. Med. and Parisitol., 39, 139 (1945).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
SIMPSON, J., SCHOFIELD, K. Antimalarial Action of Cinnoline Derivatives. Nature 157, 439–440 (1946). https://doi.org/10.1038/157439c0
Issue Date:
DOI: https://doi.org/10.1038/157439c0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.