Abstract
BY studying the simultaneous segregation of several genes in multiple heterozygotes, chromosome maps have been constructed for Drosophila, Zea and a few other organisms, and it has been shown that the order of the genes so deduced corresponds to a physical reality. It seemed likely that such maps could only be constructed very slowly for man, since very few pedigrees record the segregation of more than one gene at a time. In spite of this, indications of linkage between pairs of autosomal genes have been secured by Penrose1 and Bell2.
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References
Penrose, Ann. Eugen., 6 (1935).
Bell, Treas. Human Inher., 4 (1936).
Koller and Darlington, J. Gen., 29, 159.
Bernstein, Z. Abst. Vererb., 5 (1931).
Fisher, Ann. Eugen. (in the press).
Bell, Treas. Human Inher., 2 (1933).
Komai, ” Pedigrees of Hered. Dis. and Abnormals, found in the Japanese Race”. Kyoto (1934).
Cockayne, ” Inherited Abnormalities of the Skin and its Appendages”. Oxford (1933).
Siemens and Kohn, Z. Abst. Vererb., 38 (1925).
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HALDANE, J. A Provisional Map of a Human Chromosome. Nature 137, 398–400 (1936). https://doi.org/10.1038/137398b0
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DOI: https://doi.org/10.1038/137398b0
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