Letter | Published:

Alleged strogenic Activity of the Male Sex Hormone

Nature volume 135, page 234 (09 February 1935) | Download Citation



CORRELATION of molecular structure of the sex hormones with that of the sterols and bile acids is now almost complete, and leads to the conclusion that the hormones are biological degradation products of cholesterol. Adopting the working hypothesis that the male hormone (androsterone) is the immediate precursor of the female hormone (“strone), a study of the action of various tissue extracts on androsterone has been commenced in the hope of converting this hormone into “strone by biochemical means. The “strus test gives a very sensitive method of detecting any such conversion.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1.

    and , C.R. Soc. Biol., 99, 41; 1928.

  2. 2.

    and , Pol. Gaz. Lek., Nr. 18; 1934. , NATURE, 134, 627; 1934.

  3. 3.

    , , , and , Helv. Chim. Acta, 17, 1395; 1934.

Download references

Author information


  1. Research Institute, The Cancer Hospital (Free), London, S.W.3.

    • F. L. WARREN


  1. Search for F. L. WARREN in:

About this article

Publication history




Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.