Letter | Published:

Alleged strogenic Activity of the Male Sex Hormone

Nature volume 135, page 234 (09 February 1935) | Download Citation

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Abstract

CORRELATION of molecular structure of the sex hormones with that of the sterols and bile acids is now almost complete, and leads to the conclusion that the hormones are biological degradation products of cholesterol. Adopting the working hypothesis that the male hormone (androsterone) is the immediate precursor of the female hormone (“strone), a study of the action of various tissue extracts on androsterone has been commenced in the hope of converting this hormone into “strone by biochemical means. The “strus test gives a very sensitive method of detecting any such conversion.

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References

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Affiliations

  1. Research Institute, The Cancer Hospital (Free), London, S.W.3.

    • F. L. WARREN

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DOI

https://doi.org/10.1038/135234b0

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