Volume 42 Issue 5, May 2021

Drp1 can be SUMOylated by both SUMO-1 and SUMO-2/3. SUMO-1-ylation and deSUMO-2/3-ylation of Drp1 promotes its association with mitochondrial outer membrane (MOM), which facilitates mitochondrial fission and activates mitophagy. On the contrary, SUMO-2/3-ylation and deSUMO-1-ylation of Drp1 lead to accumulation of defective mitochondria and cardiomyocyte apoptosis.

Review Article

Drp1-dependent mitochondrial fission in cardiovascular disease

Jia-yu Jin
Xiang-xiang Wei
Dan Meng
Review Article 10 Sept 2020
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Article

Pyrroloquinoline quinone promotes mitochondrial biogenesis in rotenone-induced Parkinson’s disease model via AMPK activation

Qiong Cheng
Juan Chen
Fei Ding
Article 28 Aug 2020
β-arrestin 2 is essential for fluoxetine-mediated promotion of hippocampal neurogenesis in a mouse model of depression

Chen-xin Li
Ying Zheng
Ming Lu
Article 01 Feb 2021
Mzb1 protects against myocardial infarction injury in mice via modulating mitochondrial function and alleviating inflammation

Lu Zhang
Yi-ning Wang
Bao-feng Yang
Article 05 Aug 2020
Baicalein attenuates cardiac hypertrophy in mice via suppressing oxidative stress and activating autophagy in cardiomyocytes

Bing-yan Liu
Ling Li
Jian-xun Wang
Article 14 Aug 2020
MicroRNA-99b-3p promotes angiotensin II-induced cardiac fibrosis in mice by targeting GSK-3β

You-hui Yu
Yu-hong Zhang
Jian-tao Ye
Article 19 Aug 2020
Ruscogenin attenuates particulate matter-induced acute lung injury in mice via protecting pulmonary endothelial barrier and inhibiting TLR4 signaling pathway

Yu-wei Wang
Yun-hao Wu
Yuan-yuan Zhang
Article 27 Aug 2020
Berberine improves intralipid-induced insulin resistance in murine

Zhen-hua Dong
Hai-yan Lin
Jia-jun Zhao
Article 07 Aug 2020
Oridonin ameliorates inflammation-induced bone loss in mice via suppressing DC-STAMP expression

Bin-hua Zou
Yan-hui Tan
Xiao-juan Li
Article 04 Aug 2020
Deficiency of β-arrestin2 exacerbates inflammatory arthritis by facilitating plasma cell formation

In the course of disease, TLR4 of the B lymphocyte membrane is stimulated by ligands to activate downstream NF-κB signaling, which eventually leads to the activation of B lymphocytes and their differentiation into plasma cells and then to the production of a large number of autoantibodies. The present work reveals that β-arr2 interacts with TLR4 and mediates its endocytosis, thus inhibiting downstream NF-κB signaling mediated by TLR4 and preventing B lymphocytes from overactivation and differentiation under stimulation with inflammatory mediators

Wei-jie Zhou
Dan-dan Wang
Wei Wei
Article 27 Aug 2020
Carnosine suppresses human glioma cells under normoxic and hypoxic conditions partly via inhibiting glutamine metabolism

Yu-jia Fang
Ming Wu
Yao Shen
Article 11 Aug 2020
A novel Diels–Alder adduct of mulberry leaves exerts anticancer effect through autophagy-mediated cell death

Yu-han Shu
Hua-hua Yuan
Jian-bin Zhang
Article 19 Aug 2020
10,11-dehydrocurvularin exerts antitumor effect against human breast cancer by suppressing STAT3 activation

Qun Zhao
Yun Bi
Xian-jun Yu
Article 31 Aug 2020
Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B

Zheng Wang
Zeng-xia Li
Yong-jun Dang
Article 14 Aug 2020
Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma

Xiao-tuan Zhang
Xiao-bei Hu
Jia Li
Article 27 Aug 2020
Feasibility study of ⁶⁸Ga-labeled CAR T cells for in vivo tracking using micro-positron emission tomography imaging

Xin-yu Wang
Yan Wang
Min Yang
Article 08 Sept 2020
Lipid/PAA-coated mesoporous silica nanoparticles for dual-pH-responsive codelivery of arsenic trioxide/paclitaxel against breast cancer cells

Bing-bing Zhang
Xiao-jie Chen
Fan-zhu Li
Article 06 Apr 2021

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Correction

Publisher Correction: ‘TRAIL-based gene delivery and therapeutic strategies’ and ‘Overview of recent advances in liposomal nanoparticle-based cancer immunotherapy’

Hui-ha Zhong
Hui-yuan Wang
Hai-jun Yu
Correction Open Access 06 Jul 2020
Publisher Correction: 10.1038/s41401-020-0400-z,10.1038/s41401-020-0414-6,10.1038/s41401-020-0372-z

Correction 03 Aug 2020

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Volume 42 Issue 5, May 2021

Review Article

Drp1-dependent mitochondrial fission in cardiovascular disease

Article

Pyrroloquinoline quinone promotes mitochondrial biogenesis in rotenone-induced Parkinson’s disease model via AMPK activation

β-arrestin 2 is essential for fluoxetine-mediated promotion of hippocampal neurogenesis in a mouse model of depression

Mzb1 protects against myocardial infarction injury in mice via modulating mitochondrial function and alleviating inflammation

Baicalein attenuates cardiac hypertrophy in mice via suppressing oxidative stress and activating autophagy in cardiomyocytes

MicroRNA-99b-3p promotes angiotensin II-induced cardiac fibrosis in mice by targeting GSK-3β

Ruscogenin attenuates particulate matter-induced acute lung injury in mice via protecting pulmonary endothelial barrier and inhibiting TLR4 signaling pathway

Berberine improves intralipid-induced insulin resistance in murine

Oridonin ameliorates inflammation-induced bone loss in mice via suppressing DC-STAMP expression

Deficiency of β-arrestin2 exacerbates inflammatory arthritis by facilitating plasma cell formation

Carnosine suppresses human glioma cells under normoxic and hypoxic conditions partly via inhibiting glutamine metabolism

A novel Diels–Alder adduct of mulberry leaves exerts anticancer effect through autophagy-mediated cell death

10,11-dehydrocurvularin exerts antitumor effect against human breast cancer by suppressing STAT3 activation

Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B

Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma

Feasibility study of ⁶⁸Ga-labeled CAR T cells for in vivo tracking using micro-positron emission tomography imaging

Lipid/PAA-coated mesoporous silica nanoparticles for dual-pH-responsive codelivery of arsenic trioxide/paclitaxel against breast cancer cells

Correction

Publisher Correction: ‘TRAIL-based gene delivery and therapeutic strategies’ and ‘Overview of recent advances in liposomal nanoparticle-based cancer immunotherapy’

Publisher Correction: 10.1038/s41401-020-0400-z,10.1038/s41401-020-0414-6,10.1038/s41401-020-0372-z

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