Featured
-
-
Article
| Open AccessClinical pattern of failure after a durable response to immune checkpoint inhibitors in non-small cell lung cancer patients
- Ja Yoon Heo
- , Shin Hye Yoo
- & Jong Seok Lee
-
Article
| Open AccessMeta-analysis of host transcriptional responses to SARS-CoV-2 infection reveals their manifestation in human tumors
- Fengju Chen
- , Yiqun Zhang
- & Chad J. Creighton
-
Article
| Open AccessTumour inflammation signature and expression of S100A12 and HLA class I improve survival in HPV-negative hypopharyngeal cancer
- Michael Mints
- , David Landin
- & Torbjörn Ramqvist
-
Article
| Open AccessThe anti-tumor effects of cetuximab in combination with VTX-2337 are T cell dependent
- Yinwen Cheng
- , Nicholas Borcherding
- & Andrean L. Simons
-
Article
| Open AccessSHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms
- Ye Wang
- , Morvarid Mohseni
- & Silvia Goldoni
-
Article
| Open AccessPotential role of M2 TAMs around lymphatic vessels during lymphatic invasion in papillary thyroid carcinoma
- Takanobu Kabasawa
- , Rintaro Ohe
- & Mitsunori Yamakawa
-
Article
| Open AccessDivergent immune landscapes of primary and syngeneic Kras-driven mouse tumor models
- Wade R. Gutierrez
- , Amanda Scherer
- & Rebecca D. Dodd
-
Article
| Open AccessPrognostic relevance of programmed cell death 1 ligand 2 (PDCD1LG2/PD-L2) in patients with advanced stage colon carcinoma treated with chemotherapy
- Kevin Chih-Yang Huang
- , Shu-Fen Chiang
- & K. S. Clifford Chao
-
Article
| Open AccessActivation of T helper cells in sentinel node predicts poor prognosis in oral squamous cell carcinoma
- Åsa Kågedal
- , Eric Hjalmarsson
- & Lars Olaf Cardell
-
Article
| Open AccessPan-cancer analysis of genomic properties and clinical outcome associated with tumor tertiary lymphoid structure
- Ziying Lin
- , Lixia Huang
- & Yanbin Zhou
-
Article
| Open AccessPhoton versus carbon ion irradiation: immunomodulatory effects exerted on murine tumor cell lines
- Laura Hartmann
- , Philipp Schröter
- & Stefan B. Eichmüller
-
Article
| Open AccessQuantitative and functional characteristics of circulating and bone marrow PD-1- and TIM-3-positive T cells in treated multiple myeloma patients
- Egor V. Batorov
- , Tatiana A. Aristova
- & Elena R. Chernykh
-
Article
| Open AccessNod2 protects mice from inflammation and obesity-dependent liver cancer
- Serdar A. Gurses
- , Sunil Banskar
- & Dipika Gupta
-
Article
| Open AccessIdentification of immune-related genes as prognostic factors in bladder cancer
- Jie Zhu
- , Han Wang
- & Yue-Qing Huang
-
Article
| Open AccessDistinct regional ontogeny and activation of tumor associated macrophages in human glioblastoma
- Alexander P. Landry
- , Michael Balas
- & Zsolt Zador
-
Article
| Open AccessCharacterization of somatic mutation-associated microenvironment signatures in acute myeloid leukemia patients based on TCGA analysis
- Jun Wang
- , Feng-Ting Dao
- & Ya-Zhen Qin
-
Article
| Open AccessHepatobiliary malignancies have distinct peripheral myeloid-derived suppressor cell signatures and tumor myeloid cell profiles
- Defne Bayik
- , Adam J. Lauko
- & Justin D. Lathia
-
Article
| Open AccessCombining multiple spatial statistics enhances the description of immune cell localisation within tumours
- Joshua A. Bull
- , Philip S. Macklin
- & Helen M. Byrne
-
Article
| Open AccessIn vitro antitumor, pro-inflammatory, and pro-coagulant activities of Megalopyge opercularis J.E. Smith hemolymph and spine venom
- Alonso A. Orozco-Flores
- , José A. Valadez-Lira
- & Patricia Tamez-Guerra
-
Article
| Open AccessA role for the immune system in advanced laryngeal cancer
- Marta Tagliabue
- , Fausto Maffini
- & Mohssen Ansarin
-
Article
| Open AccessRole of locoregional surgery in patients with de novo stage IV breast cancer: analysis of real-world data from China
- Li Ma
- , Yunzhe Mi
- & Zefei Jiang
-
Article
| Open AccessBaseline IFN-γ and IL-10 expression in PBMCs could predict response to PD-1 checkpoint inhibitors in advanced melanoma patients
- Emilio Francesco Giunta
- , Giusi Barra
- & Teresa Troiani
-
Article
| Open AccessHigher cytolytic score correlates with an immunosuppressive tumor microenvironment and reduced survival in glioblastoma
- Alexander F. Haddad
- , Jia-Shu Chen
- & Manish K. Aghi
-
Article
| Open AccessTAS0314, a novel multi-epitope long peptide vaccine, showed synergistic antitumor immunity with PD-1/PD-L1 blockade in HLA-A*2402 mice
- Yuki Tanaka
- , Hiroshi Wada
- & Teruhiro Utsugi
-
Article
| Open AccessMicroRNA-340-5p inhibits colon cancer cell migration via targeting of RhoA
- Anwar Algaber
- , Amr Al-Haidari
- & Henrik Thorlacius
-
Article
| Open AccessChronic lymphocytic leukemia-associated paraneoplastic pemphigus: potential cause and therapeutic strategies
- Lei Cao
- , Fei Wang
- & Lei Fan
-
Article
| Open AccessLandscape of immune checkpoint inhibitor-related adverse events in Chinese population
- Li Li
- , Gang Li
- & Yao-Zhong Wu
-
Article
| Open AccessThe fatty-acid amide hydrolase inhibitor URB597 inhibits MICA/B shedding
- Kazuma Sekiba
- , Motoyuki Otsuka
- & Kazuhiko Koike
-
Article
| Open AccessMolecular subtyping of glioblastoma based on immune-related genes for prognosis
- Xueran Chen
- , Xiaoqing Fan
- & Zhiyou Fang
-
Article
| Open AccessExtracellular vesicles produced by immunomodulatory cells harboring OX40 ligand and 4-1BB ligand enhance antitumor immunity
- Isadora Ferraz Semionatto
- , Soledad Palameta
- & Marcio Chaim Bajgelman
-
Article
| Open AccessAn engineered antibody binds a distinct epitope and is a potent inhibitor of murine and human VISTA
- Nishant Mehta
- , Sainiteesh Maddineni
- & Jennifer R. Cochran
-
Article
| Open AccessDysfunction of CD8 + PD-1 + T cells in type 2 diabetes caused by the impairment of metabolism-immune axis
- Ichiro Nojima
- , Shingo Eikawa
- & Jun Wada
-
Article
| Open AccessHigh MHC-II expression in Epstein–Barr virus-associated gastric cancers suggests that tumor cells serve an important role in antigen presentation
- Farhad Ghasemi
- , Tanner M. Tessier
- & Joe S. Mymryk
-
Article
| Open AccessImmune suppressed tumor microenvironment by exosomes derived from gastric cancer cells via modulating immune functions
- Juan Liu
- , Shaoxian Wu
- & Jingting Jiang
-
Article
| Open AccessModerate static magnetic fields enhance antitumor CD8+ T cell function by promoting mitochondrial respiration
- Xiaoyan Zhu
- , Yan Liu
- & Qiwei Zhai
-
Article
| Open AccessEvaluation of cytotoxic T lymphocyte-mediated anticancer response against tumor interstitium-simulating physical barriers
- Shu-Ching Chen
- , Po-Cheng Wu
- & Po-Ling Kuo
-
Article
| Open AccessHepatocellular carcinoma-derived high mobility group box 1 triggers M2 macrophage polarization via a TLR2/NOX2/autophagy axis
- Dong-Jer Shiau
- , Wan-Ting Kuo
- & Chih-Peng Chang
-
Article
| Open AccessPrognostic value of neutrophil-to-lymphocyte ratio in human epidermal growth factor receptor 2-negative breast cancer patients who received neoadjuvant chemotherapy
- Soong June Bae
- , Yoon Jin Cha
- & Joon Jeong
-
Article
| Open AccessIL-21 Stimulates the expression and activation of cell cycle regulators and promotes cell proliferation in EBV-positive diffuse large B cell lymphoma
- Yuxuan Wang
- , Chengcheng Wang
- & Liang Wu
-
Article
| Open AccessTumor microenvironment characterization in head and neck cancer identifies prognostic and immunotherapeutically relevant gene signatures
- Mengqi Huo
- , Ying Zhang
- & Tianke Li
-
Article
| Open AccessIncreased both PD–L1 and PD–L2 expressions on monocytes of patients with hepatocellular carcinoma was associated with a poor prognosis
- Hidetaka Yasuoka
- , Akira Asai
- & Kazuhide Higuchi
-
Article
| Open AccessGlioM&M: Web-based tool for studying circulating and infiltrating monocytes and macrophages in glioma
- Erik R. Abels
- , Sybren L. N. Maas
- & Joseph El Khoury
-
Article
| Open AccessThe tumor immune microenvironmental analysis of 2,033 transcriptomes across 7 cancer types
- Sungjae Kim
- , Ahreum Kim
- & Jeong-Sun Seo
-
Article
| Open AccessIn silico analysis reveals EP300 as a panCancer inhibitor of anti-tumor immune response via metabolic modulation
- Rosemarie Krupar
- , Christian Watermann
- & Sven Perner
-
Article
| Open AccessPeripheral natural killer cells and myeloid-derived suppressor cells correlate with anti-PD-1 responses in non-small cell lung cancer
- Je-In Youn
- , Su-Myeong Park
- & Hye Ryun Kim
-
Article
| Open AccessGATA2 Regulates Constitutive PD-L1 and PD-L2 Expression in Brain Tumors
- Yujie Fu
- , Connor J. Liu
- & Gavin P. Dunn
-
Article
| Open AccessSoluble programmed death-ligand 1 rather than PD-L1 on tumor cells effectively predicts metastasis and prognosis in soft tissue sarcomas
- Kunihiro Asanuma
- , Tomoki Nakamura
- & Akihiro Sudo
-
Article
| Open AccessRapid conjugation of antibodies to toxins to select candidates for the development of anticancer Antibody-Drug Conjugates (ADCs)
- Ricarda M. Hoffmann
- , Silvia Mele
- & Silvia Crescioli
-
Article
| Open AccessCharacterization of tumour-infiltrating lymphocytes in a tumour rejection cynomolgus macaque model
- Hiroki Satooka
- , Hirohito Ishigaki
- & Takako Hirata