Brief Communications Arising |
Featured
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Brief Communications Arising |
Improving outcomes in congenital cataract
- Ameenat Lola Solebo
- , Christopher J. Hammond
- & Jugnoo S. Rahi
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News |
First road map of human sex-cell development
Study marks a step towards stem-cell treatment of infertility.
- Becky Summers
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News |
Human embryonic stem cells restore gerbil hearing
Study offers first proof that stem cells can reconnect inner ear to brain.
- Virginia Gewin
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Letter |
Restoration of auditory evoked responses by human ES-cell-derived otic progenitors
Two types of human ES-cell-derived otic progenitors are shown to have the ability to differentiate in vitro into hair-cell-like cells and auditory neurons, and to engraft, differentiate and improve auditory-evoked response thresholds when transplanted into an auditory neuropathy model; this indicates that it may be possible to use cell-based therapeutic strategies to recover damaged sensory circuitry in deafness.
- Wei Chen
- , Nopporn Jongkamonwiwat
- & Marcelo N. Rivolta
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News |
Stem-cell pioneer banks on future therapies
Japanese researcher plans cache of induced stem cells to supply clinical trials.
- David Cyranoski
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News |
FDA’s claims over stem cells upheld
Drug watchdog wins right to regulate controversial therapies.
- David Cyranoski
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News & Views |
One step closer to gut repair
The use of adult-tissue stem cells to treat gastrointestinal diseases holds much promise. A method for in vitro growth of gut stem cells and their use in repairing damaged intestines in mice has been described.
- Anisa Shaker
- & Deborah C. Rubin
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Editorial |
Buyer beware
An investigation by Nature shows the scale of the market for unapproved stem-cell therapies in China. Hype and unrealistic hope must not be allowed to undermine genuine promise.
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News |
China’s stem-cell rules go unheeded
Health ministry’s attempt at regulation has had little effect.
- David Cyranoski
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Outlook |
Stem cells: Don't believe the hype
Researchers are still a long way from using stem cells to halt the decline caused by multiple sclerosis and to restore patients' health. But they are following some promising trails.
- Michael Eisenstein
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Editorial |
The darker side of stem cells
An investigation by Nature has found that patients in Texas are receiving unproven stem-cell treatments. The state and the company involved need to ensure that they follow FDA guidelines.
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News |
Stem-cell therapy takes off in Texas
A boom in unproven procedures is worrying scientists.
- David Cyranoski
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Research Highlights |
Restore my beating heart
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News |
Editor’s move sparks backlash
Bioethicists are forced to consider their purpose as leading practitioner joins controversial stem-cell company.
- David Cyranoski
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Review Article |
The promise of induced pluripotent stem cells in research and therapy
- Daisy A. Robinton
- & George Q. Daley
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News Feature |
Stem-cell research: Never say die
With a history of public blunders, can Advanced Cell Technology make embryonic stem-cell therapies a reality?
- Corie Lok
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Outlook |
Stem cells: Transplants on trial
Stem-cell transplants are an important tool for treating myeloma. But with improved drug alternatives, doctors disagree about the best time to give the treatment.
- Elie Dolgin
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News |
Stem cells that are pure enough for the clinic
High-quality human embryonic stem cells derived without the use of animal products.
- Ewen Callaway
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News |
European court bans patents based on embryonic stem cells
Final decision could stifle investment in developing therapies.
- Ewen Callaway
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Letter |
Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells
- Kosuke Yusa
- , S. Tamir Rashid
- & Ludovic Vallier
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News |
Texas prepares to fight for stem cells
Enthusiasm for unapproved treatments worries regulators.
- David Cyranoski
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Letter |
Direct generation of functional dopaminergic neurons from mouse and human fibroblasts
- Massimiliano Caiazzo
- , Maria Teresa Dell’Anno
- & Vania Broccoli
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News |
Stem-cell scientists grapple with clinics
In the absence of regulation, researchers weigh their options for educating patients about unproven treatments.
- Heidi Ledford
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News |
Reprogrammed cells trigger immune reactions in mice
Medical applications of induced pluripotent stem cells called into question.
- Erika Check Hayden
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News |
Korean deaths spark inquiry
Cases highlight the challenge of policing multinational trade in stem-cell treatments.
- David Cyranoski
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News |
There will be blood
Direct conversion of cell types could offer safer, simpler treatments than stem cells.
- Ewen Callaway
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News & Views |
An eye to treating blindness
Work on stem cells is one of the hottest research areas in biology. But are such studies of any therapeutic value? Fortunately, yes, as is evident from successes in treating blindness.
- Elena Ezhkova
- & Elaine Fuchs
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Editorial |
Order from chaos
Much tighter regulations are needed to reap the full benefits of stem-cell treatments.
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News |
Strange lesions after stem-cell therapy
Unproven treatment results in mysterious masses.
- David Cyranoski
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Research Highlights |
Regenerative biology: New nerve cells connect
Stricter management of organ transplants