Cell therapies articles within Nature

Featured

• Perspective | 22 February 2023

  CAR immune cells: design principles, resistance and the next generation

  This Perspective reviews recent developments in the design and use of chimeric antigen receptors in treatments for cancers and other diseases.

  • Louai Labanieh
  •  & Crystal L. Mackall

• Article
  31 August 2022 | Open Access

  Non-viral, specifically targeted CAR-T cells achieve high safety and efficacy in B-NHL

  Non-viral CAR-T cells with gene-specific targeted integration are safe and effective in patients with lymphoma.

  • Jiqin Zhang
  • , Yongxian Hu
  •  & He Huang

• Letter | 10 October 2012

  Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation

  A genetically engineered mouse model is used to determine the mechanism of acquired resistance to adoptive therapy with cytotoxic T cells specific for a melanocytic differentiation antigen; tumour necrosis factor (TNF)-α is identified as a crucial factor that causes reversible dedifferentiation of mouse and human melanoma cells.

  • Jennifer Landsberg
  • , Judith Kohlmeyer
  •  & Thomas Tüting

• News | 07 August 2012

  Stem-cell pioneer banks on future therapies

  Japanese researcher plans cache of induced stem cells to supply clinical trials.

  • David Cyranoski

• News | 27 July 2012

  FDA’s claims over stem cells upheld

  Drug watchdog wins right to regulate controversial therapies.

  • David Cyranoski

• News Feature | 11 January 2012

  Stem-cell research: Never say die

  With a history of public blunders, can Advanced Cell Technology make embryonic stem-cell therapies a reality?

  • Corie Lok

• Research Highlights | 09 November 2011

  Safety switch for cell therapy

• News | 18 October 2011

  European court bans patents based on embryonic stem cells

  Final decision could stifle investment in developing therapies.

  • Ewen Callaway

• Research Highlights | 21 September 2011

  Heart attack hits bone marrow

• News | 20 September 2011

  Texas prepares to fight for stem cells

  Enthusiasm for unapproved treatments worries regulators.

  • David Cyranoski

• News | 10 August 2011

  Cell therapy fights leukaemia

  Patchwork receptors target immune cells against cancer.

  • Heidi Ledford

• News | 28 June 2011

  Stem-cell scientists grapple with clinics

  In the absence of regulation, researchers weigh their options for educating patients about unproven treatments.

  • Heidi Ledford

• News | 13 May 2011

  Reprogrammed cells trigger immune reactions in mice

  Medical applications of induced pluripotent stem cells called into question.

  • Erika Check Hayden

• Research Highlights | 27 January 2010

  Regenerative biology: New nerve cells connect