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| Open AccessHuman pluripotent stem cell-based models suggest preadipocyte senescence as a possible cause of metabolic complications of Werner and Bloom Syndromes
- Kim Jee Goh
- , Jian-Hua Chen
- & Robert K. Semple
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| Open AccessPhenotypic and functional characterization of corneal endothelial cells during in vitro expansion
- Ricardo F. Frausto
- , Vinay S. Swamy
- & Anthony J. Aldave
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| Open AccessVariation of 4 MV X-ray dose rate strongly impacts biological response both in vitro and in vivo
- M. Ben Kacem
- , M. A. Benadjaoud
- & V. Paget
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| Open AccessS-Phase Kinase-associated Protein-2 Rejuvenates Senescent Endothelial Progenitor Cells and Induces Angiogenesis in Vivo
- Hsueh-Hsiao Wang
- , Yi-Nan Lee
- & Yih-Jer Wu
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| Open AccessCigarette smoking induces human CCR6+Th17 lymphocytes senescence and VEGF-A secretion
- Indoumady Baskara
- , Stéphane Kerbrat
- & Sabine Le Gouvello
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| Open AccessResveratrol and its Related Polyphenols Contribute to the Maintenance of Genome Stability
- Yusuke Matsuno
- , Yuko Atsumi
- & Ken-ichi Yoshioka
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| Open AccessChronic irradiation of human cells reduces histone levels and deregulates gene expression
- Donna J. Lowe
- , Mareike Herzog
- & Stephen P. Jackson
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| Open AccessSynergistic effects of repair, resilience and retention of damage determine the conditions for replicative ageing
- Johannes Borgqvist
- , Niek Welkenhuysen
- & Marija Cvijovic
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| Open AccessIncreased double strand breaks in diabetic β-cells with a p21 response that limits apoptosis
- Vanessa S. Y. Tay
- , Surabhi Devaraj
- & Yusuf Ali
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| Open AccessLife-span extension by pigmented rice bran in the model yeast Saccharomyces cerevisiae
- Pitchapat Sunthonkun
- , Rinsai Palajai
- & Nitnipa Soontorngun
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| Open AccessFanconi anemia proteins counteract the implementation of the oncogene-induced senescence program
- Anne Helbling-Leclerc
- , Françoise Dessarps-Freichey
- & Filippo Rosselli
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| Open AccessDepletion of Mitochondrial DNA in Differentiated Retinal Pigment Epithelial Cells
- Xinqian Hu
- , Melissa A. Calton
- & Douglas Vollrath
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| Open AccessMultiparametric radiobiological assays show that variation of X-ray energy strongly impacts relative biological effectiveness: comparison between 220 kV and 4 MV
- Vincent Paget
- , Mariam Ben Kacem
- & Fabien Milliat
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| Open AccessIdentification of reference genes for RT-qPCR data normalisation in aging studies
- Lourdes González-Bermúdez
- , Teresa Anglada
- & Mariona Terradas
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| Open AccessConstitutive PGC-1α overexpression in skeletal muscle does not protect from age-dependent decline in neurogenesis
- Lars Karlsson
- , María Nazareth González-Alvarado
- & Hans Georg Kuhn
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| Open AccessReversibility of Age-related Oxidized Free NADH Redox States in Alzheimer’s Disease Neurons by Imposed External Cys/CySS Redox Shifts
- Yue Dong
- , Sara Sameni
- & Gregory J. Brewer
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| Open AccessSexually dimorphic leanness and hypermobility in p16Ink4a/CDKN2A-deficient mice coincides with phenotypic changes in the cerebellum
- Kwang H. Kim
- , Yejin Cho
- & Ki Taek Nam
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| Open AccessHyaluronan abrogates imatinib-induced senescence in chronic myeloid leukemia cell lines
- Silvina Lompardía
- , Mariángeles Díaz
- & Silvia Hajos
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| Open AccessThe roles of p38 MAPK → COX2 and NF-κB → COX2 signal pathways in age-related testosterone reduction
- Yu Zhao
- , Xuehui Liu
- & Pin Lv
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| Open AccessShort exposure to cold atmospheric plasma induces senescence in human skin fibroblasts and adipose mesenchymal stromal cells
- Marion Bourdens
- , Yannick Jeanson
- & Valérie Planat-Bénard
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| Open AccessShortened leukocyte telomere length is associated with reduced pulmonary function and greater subsequent decline in function in a sample of World Trade Center responders
- Sean A. P. Clouston
- , Norman H. Edelman
- & Benjamin J. Luft
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| Open AccessTGFβ2-induced senescence during early inner ear development
- Alejandro Gibaja
- , María R. Aburto
- & Marta Magariños
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| Open AccessGRSF1 is an age-related regulator of senescence
- Su-Jeong Kim
- , Maria Chun
- & Pinchas Cohen
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| Open AccessCytoprotective effects of Avenathramide C against oxidative and inflammatory stress in normal human dermal fibroblasts
- Chenxuan Wang
- & Christopher H. Eskiw
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| Open AccessMetabolism as an early predictor of DPSCs aging
- Dannie Macrin
- , Ammar Alghadeer
- & Hannele Ruohola-Baker
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| Open AccessAutofluorescence is a Reliable in vitro Marker of Cellular Senescence in Human Mesenchymal Stromal Cells
- Alessandro Bertolo
- , Martin Baur
- & Jivko Stoyanov
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| Open AccessDownregulation of PRMT1 promotes the senescence and migration of a non-MYCN amplified neuroblastoma SK-N-SH cells
- Yu-Jen Lee
- , Wen-Wei Chang
- & Chuan Li
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| Open AccessSIX1 represses senescence and promotes SOX2-mediated cellular plasticity during tumorigenesis
- Cristina De Lope
- , Samara Martín-Alonso
- & Ignacio Palmero
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| Open AccessHigh doses of synthetic antioxidants induce premature senescence in cultivated mesenchymal stem cells
- Ju. S. Kornienko
- , I. S. Smirnova
- & O. G. Lyublinskaya
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| Open AccessSuppression of SIRT1 in Diabetic Conditions Induces Osteogenic Differentiation of Human Vascular Smooth Muscle Cells via RUNX2 Signalling
- F. Bartoli-Leonard
- , F. L. Wilkinson
- & R. Weston
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| Open AccessReduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis
- María Rodríguez-Hidalgo
- , Marta Luna-Sánchez
- & Luis C. López
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| Open AccessBovine telomere dynamics and the association between telomere length and productive lifespan
- Luise A. Seeker
- , Joanna J. Ilska
- & Georgios Banos
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| Open AccessCellular Uptake and Bioavailability of Tocotrienol-Rich Fraction in SIRT1-Inhibited Human Diploid Fibroblasts
- Faizul Jaafar
- , Asmaa Abdullah
- & Suzana Makpol
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| Open AccessRETRACTED ARTICLE: The Na/K-ATPase Oxidant Amplification Loop Regulates Aging
- Komal Sodhi
- , Alexandra Nichols
- & Joseph I. Shapiro
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| Open AccessDNA damage response induced by Etoposide promotes steroidogenesis via GADD45A in cultured adrenal cells
- Mimi Tamamori-Adachi
- , Akane Koga
- & Tomoki Okazaki
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| Open AccessQuantitative SUMO proteomics reveals the modulation of several PML nuclear body associated proteins and an anti-senescence function of UBC9
- Francis P. McManus
- , Véronique Bourdeau
- & Pierre Thibault
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| Open AccessErythrocyte’s aging in microgravity highlights how environmental stimuli shape metabolism and morphology
- S. Dinarelli
- , G. Longo
- & M. Girasole
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| Open AccessSmall-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype
- Christopher D. Wiley
- , Nicholas Schaum
- & Judith Campisi
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| Open AccessDown-regulation of guanylate binding protein 1 causes mitochondrial dysfunction and cellular senescence in macrophages
- Xiaoxue Qiu
- , Hong Guo
- & Xiaoli Chen
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| Open AccessTelomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data
- James H. R. Farmery
- , Mike L. Smith
- & Andy G. Lynch
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| Open AccessHPV-16 virions can remain infectious for 2 weeks on senescent cells but require cell cycle re-activation to allow virus entry
- Justyna Broniarczyk
- , Nadja Ring
- & Lawrence Banks
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| Open AccessLoss of lamin B1 is a biomarker to quantify cellular senescence in photoaged skin
- Audrey Shimei Wang
- , Peh Fern Ong
- & Oliver Dreesen
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| Open AccessDivergent roles for Clusterin in Lung Injury and Repair
- David M. Habiel
- , Ana Camelo
- & Lynne A. Murray
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| Open AccessLate-onset Alzheimer’s disease is associated with inherent changes in bioenergetics profiles
- Kai-C. Sonntag
- , Woo-In Ryu
- & Bruce M. Cohen
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| Open AccessCdk2 strengthens the intra-S checkpoint and counteracts cell cycle exit induced by DNA damage
- Katarina Bačević
- , Gérald Lossaint
- & Vjekoslav Dulić
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| Open AccessThe contribution of Saccharomyces cerevisiae replicative age to the variations in the levels of Trx2p, Pdr5p, Can1p and Idh isoforms
- Aglaia V. Azbarova
- , Kseniia V. Galkina
- & Dmitry A. Knorre
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| Open Access6-bromo-indirubin-3′-oxime (6BIO), a Glycogen synthase kinase-3β inhibitor, activates cytoprotective cellular modules and suppresses cellular senescence-mediated biomolecular damage in human fibroblasts
- Aimilia D. Sklirou
- , Nicolas Gaboriaud-Kolar
- & Ioannis P. Trougakos
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| Open Access5-methoxytryptophan protects MSCs from stress induced premature senescence by upregulating FoxO3a and mTOR
- Tzu-Ching Chang
- , Min-Fen Hsu
- & Kenneth K. Wu
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| Open AccessDevelopment of new experimental platform ‘MARS’—Multiple Artificial-gravity Research System—to elucidate the impacts of micro/partial gravity on mice
- Dai Shiba
- , Hiroyasu Mizuno
- & Satoru Takahashi