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News & Views |
Non-invasive nuclear imaging for localization of viral reservoirs
Antibody-targeted positron emission tomography (immunoPET) can visualize sites of HIV replication that are difficult to access by traditional means such as tissue biopsies.
- Ekaterina Dadachova
- & Joan W Berman
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Article |
Whole-body immunoPET reveals active SIV dynamics in viremic and antiretroviral therapy–treated macaques
ImmunoPET/CT imaging using a labeled SIV-specific antibody can identify sites of viralinfection in SIV-infected macaques without the need for tissue biopsies, even if viral load in the blood is below the detection limit.
- Philip J Santangelo
- , Kenneth A Rogers
- & Francois Villinger
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News & Views |
Functional whole-brain imaging in behaving rodents
A wearable imaging device allows functional whole-brain imaging of awake, freely moving rats. This technology opens up a noninvasive window for simultaneously assessing brain function and behavior in response to a wide variety of interventions in living rats.
- Simon R Cherry
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Article |
Simultaneous assessment of rodent behavior and neurochemistry using a miniature positron emission tomograph
A miniature portable tomograph allows the imaging of awake, behaving rats with positron emission tomography while simultaneously measuring their behavior. This method for noninvasive whole-brain imaging can link studies of brain activity with particular behaviors.
- Daniela Schulz
- , Sudeepti Southekal
- & Paul Vaska
In vivo detection of antigen-specific CD8+ T cells by immuno-positron emission tomography