Research Highlight |
Featured
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News & Views |
Health burden in cancer survivors: below the tip of the iceberg
In recent decades, cancer survival has improved dramatically, resulting in a growing population of cancer survivors with chronic health needs and disease risks. While large epidemiological studies are useful in tracking broad trends in health outcomes of cancer survivors, they lack the level of detail needed to inform the delivery of appropriate clinical care and optimal allocation of resources.
- Eden R. Brauer
- & Patricia A. Ganz
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Comment |
Bridging the gap: are animal models consistent with clinical cancer cachexia?
Experimental research on cancer-associated cachexia is advancing at an accelerated pace while knowledge of the complex underlying biology of cachexia in humans lags behind. An unmet need exists to accelerate the identification of causal mechanisms in patients with cancer and to determine the parallels between experimental systems and distinct isotypes of human cachexia.
- Vickie E. Baracos
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Review Article |
Exogenous reproductive hormone use in breast cancer survivors and previvors
The safety of elective exogenous hormonal exposure among breast cancer survivors or women at high risk of having the disease has been debated for decades. Herein, the authors discuss the available data and present clinical recommendations regarding four areas of potential exogenous exposure to hormones: hormonal contraception; systemic hormone-replacement therapy; localized hormone-replacement therapy; and hormonal manipulation for fertility preservation or enhancement. Further research is needed to improve patient management in the future.
- Ines Vaz-Luis
- & Ann H. Partridge
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