Nanoparticles articles within Nature Materials

Featured

  • Article |

    The emergence of chiral morphologies from achiral building blocks is not well understood. Deep learning-based interpretation provides representative models for the process of symmetry breaking and chiral development during the growth of gold nanoparticles.

    • Sang Won Im
    • , Dongsu Zhang
    •  & Ki Tae Nam

  • Article
    | Open Access

    Active and stable catalysts to accelerate the transition from fossil fuel to renewable feedstocks, reduce energy consumption and minimize environmental footprints are needed. Electrocatalysts based on copper nanocrystals encapsulated in hybrid alumina shells stable against structural reconstruction during CO2 electroreduction are reported.

    • Petru P. Albertini
    • , Mark A. Newton
    •  & Raffaella Buonsanti

  • Article
    | Open Access

    The self-assembly of metallic nanoparticles on oxide supports via metal exsolution relies on dopant transport, but strong electrostatic gradients and space charges typically control the properties of surfaces. The surface–dopant interaction is shown to be the main determining factor for the exsolution kinetics of nickel in a perovskite system.

    • Moritz L. Weber
    • , Břetislav Šmíd
    •  & Christian Lenser

  • News & Views |

    Engineered ligand shells on gold nanoclusters utilizing molecular motion improve the thermal conductance between the cluster and the solvent, increasing thermal stability and enhancing performance in the photothermal treatment of cancerous tumours.

    • Jacob L. Beckham
    •  & James M. Tour

  • Article |

    The rational design and assembly of colloidal quasicrystals is achieved by exploring the hybridization of nanoscale decahedra nanoparticles functionalized with DNA linkers.

    • Wenjie Zhou
    • , Yein Lim
    •  & Chad A. Mirkin

  • News & Views |

    Lymphatic vessels within and near to tumours facilitate nanoparticle transport out of tumours, with ramifications in the design and implementation of next-generation clinical cancer nanomedicines.

    • Meghan J. O’Melia
    •  & Susan N. Thomas

  • Article |

    Nanoparticle retention inside tumours has been associated with lymphatic vessel collapse. It is now shown that nanoparticles exit from solid tumours through lymphatic vessels in or surrounding the tumour by a nanoparticle-size-dependent mechanism.

    • Luan N. M. Nguyen
    • , Zachary P. Lin
    •  & Warren C. W. Chan

  • News & Views |

    A polymeric nanoparticle adjuvant containing a Toll-like receptor 7 agonist elicits broad protection against viral challenges.

    • Jorge Huete-Carrasco
    •  & Ed C. Lavelle

  • News & Views |

    A large-scale screening identifies an inhalable polymer nanoparticle formulation that safely and effectively delivers therapeutic mRNA molecules to the lungs of several animal species.

    • Ronnie H. Fang
    •  & Liangfang Zhang

  • Review Article |

    Persistent luminescent phosphors are promising for applications from bioimaging to multilevel encryption. Here, the authors review the design and preparation of persistent luminescence nanomaterials, developments in biological applications and outstanding challenges.

    • Liangliang Liang
    • , Jiaye Chen
    •  & Xiaogang Liu

  • Perspective |

    Colloidal nanocrystals can form into periodic superlattices exhibiting collective vibrations from the correlated motion of the nanocrystals. This Perspective discusses such collective vibrations and their as-of-yet untapped potential applications for phononic crystals, acoustic metamaterials and optomechanical systems.

    • Maximilian Jansen
    • , William A. Tisdale
    •  & Vanessa Wood

  • Article |

    Delivering inherently stable lithium-ion batteries with electrodes that can reversibly insert and extract large quantities of Li+ with inherent stability during cycling are key. Lithium-excess vanadium oxides with a disordered rocksalt structure are now investigated as high-capacity and long-life cathodes.

    • Itsuki Konuma
    • , Damian Goonetilleke
    •  & Naoaki Yabuuchi

  • Article |

    Metal oxide–zeolite bifunctional catalysts allow coupling of reactions and so enhance catalytic processes, but structure and reactivity control is difficult. Here, a general synthesis is presented for metal oxide–zeolite double-shelled hollow spheres, which outperform other catalysts for petroleum production.

    • Jiadong Xiao
    • , Kang Cheng
    •  & Bert M. Weckhuysen

  • Perspective |

    This Perspective discusses biological barriers that have limited clinical translation of cancer nanomedicines and elaborates on new directions for the field that capitalize on a deeper understanding of the nano–bio interface.

    • Irene de Lázaro
    •  & David J. Mooney

  • Why it Matters |

    Tebello Nyokong, Bokolombe Ngoy and Edith Amuhaya share their experiences in conducting research in Africa.

    • Tebello Nyokong
    • , Bokolombe P. Ngoy
    •  & Edith K. Amuhaya

  • News & Views |

    A dose threshold of one trillion nanoparticles in mice has been discovered and is shown to be crucial for overwhelming the nanoparticle uptake kinetics of liver Kupffer cells and for ensuring efficient nanoparticle delivery into solid tumours upon intravenous administration.

    • Twan Lammers

  • Article |

    Metallic nanoparticles used to harvest energy from a light source typically result in reduced chemical reaction temperature. Endothermic reactions requiring higher activation energy can now be initiated at room temperature using localized surface plasmons in the deep-UV range.

    • Canhui Wang
    • , Wei-Chang D. Yang
    •  & Renu Sharma

  • Article |

    Efficient nanoparticle delivery into tumours has been a challenge in the field. It is now shown that the efficiency can be improved substantially when the dose breaches a specific threshold.

    • Ben Ouyang
    • , Wilson Poon
    •  & Warren C. W. Chan

  • News & Views |

    Programmable DNA hybridization is used to mediate the self-assembly of substrate-bound DNA-grafted gold nanoparticles into single-crystalline Winterbottom and non-Winterbottom constructions with particular size, shape and orientation.

    • Chang Liu
    •  & Qian Chen

  • Editorial |

    A collective effort from materials scientists, life scientists and clinicians is required to systematically address fundamental questions in the mechanisms of nanoparticle delivery in order to overcome the hurdles in translating nanomedicines for tumour therapy.

  • Comment |

    New evidence suggests that the mechanism of nanoparticle entry into solid tumours may be driven by an active process. This insight paves the way for approaches to enhance the efficiency of nanomedicine delivery by harnessing active transport mechanisms, and encourage researchers to rethink how tumours are treated.

    • Subehndu Pandit
    • , Debapriya Dutta
    •  & Shuming Nie

  • News & Views |

    Magnetite crystals form by the aggregation and subsequent merger of crystalline precursors, which can be interpreted in terms of colloidal assembly.

    • Jeffrey D. Rimer

  • News & Views |

    Low-electron-dose liquid-cell transmission electron microscopy reveals a two-step nucleation process during the crystallization of triangular nanoplatelets in water at the single-particle level.

    • Yilong Han

  • Article |

    The dominant mechanism of nanoparticle entry into solid tumours has now been shown to be an active trans-endothelial pathway rather than the currently established passive transport via inter-endothelial gaps.

    • Shrey Sindhwani
    • , Abdullah Muhammad Syed
    •  & Warren C. W. Chan

  • Article |

    Single-stranded DNA encoders containing polyadenine domains endow colloidal gold nanoparticles with programmable bond valence, orthogonality and reconfigurability, thus achieving post-synthetic control over colloidal structures.

    • Guangbao Yao
    • , Jiang Li
    •  & Chunhai Fan

  • Letter |

    The ultrafast response of a pyroelectric sensor with near-infrared responsivity is demonstrated by combining a pyroelectric thermal detector with wavelength-selective nanoparticle absorbers.

    • Jon W. Stewart
    • , Jarrett H. Vella
    •  & Maiken H. Mikkelsen

  • Article |

    Low-dose liquid-phase transmission electron microscopy, particle tracking and numerical simulations are used to characterize the crystallization kinetics and pathways of gold nanoprisms at the single-particle level.

    • Zihao Ou
    • , Ziwei Wang
    •  & Qian Chen

  • Letter |

    The kinetics and thermodynamics of the nucleation of magnetite crystals from primary particles are shown to be described by colloidal assembly theory, allowing for predictions of crystal sizes to be made.

    • Giulia Mirabello
    • , Alessandro Ianiro
    •  & Nico A. J. M. Sommerdijk

  • Article |

    An anticancer agent, olsalazine, conjugated to a cell-penetrating peptide has been synthesized and shows the ability to self-assemble intracellularly by the tumour-associated enzyme furin, with the potential for tumour therapy and chemical exchange saturation transfer magnetic resonance imaging in vivo.

    • Yue Yuan
    • , Jia Zhang
    •  & Jeff W. M. Bulte

  • News & Views |

    The path from ordered assemblies of quantum dots to epitaxially connected quantum dot solids is revealed with X-ray scattering and electron microscopy investigations.

    • Tobias Hanrath

  • News & Views |

    Hematopoietic stem and progenitor cells have been engineered using gold nanoformulations conjugated with CRISPR capable of targeting two distinct genomic loci of therapeutic interest, with potential engraftment in humanized mouse models.

    • Aravind Asokan

  • Article |

    Sensing hydrogen by the change in plasmonic response upon metal hydride formation is safe, but trace gas poisoning and low sensitivity can occur. Here, a PdAu alloy/polymer sensor is poison resistant and can sense 3 ppm H2 with a response time of 1 s.

    • Ferry A. A. Nugroho
    • , Iwan Darmadi
    •  & Christoph Langhammer

  • News & Views |

    By combining metal ions, organic linkers and polymers, ordered frameworks with controlled crystallite size can form. When fabricated into membranes, they combine superlative CO2/N2 separation properties with good hydrolytic stability.

    • Joshua D. Moon
    •  & Benny D. Freeman

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