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| Open AccessSphingomyelin nanosystems loaded with uroguanylin and etoposide for treating metastatic colorectal cancer
- Belén L. Bouzo
- , Saínza Lores
- & María de la Fuente
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| Open AccessEffects of the sigma-1 receptor agonist blarcamesine in a murine model of fragile X syndrome: neurobehavioral phenotypes and receptor occupancy
- Samantha T. Reyes
- , Robert M. J. Deacon
- & Frederick T. Chin
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| Open AccessImpact of genetic and non-genetic factors on hepatic CYP2C9 expression and activity in Hungarian subjects
- Ferenc Fekete
- , Katalin Mangó
- & Katalin Monostory
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| Open AccessMulti-layered proteogenomic analysis unravels cancer metastasis directed by MMP-2 and focal adhesion kinase signaling
- Yumi Kwon
- , Seong-Jun Park
- & Cheolju Lee
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| Open AccessHigh-content image-based analysis and proteomic profiling identifies Tau phosphorylation inhibitors in a human iPSC-derived glutamatergic neuronal model of tauopathy
- Chialin Cheng
- , Surya A. Reis
- & Stephen J. Haggarty
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| Open AccessTranslocation of intracellular CD24 constitutes a triggering event for drug resistance in breast cancer
- Hugo Werner Huth
- , Thiago Castro-Gomes
- & Catherine Ropert
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| Open AccessIdentification of markers that distinguish adipose tissue and glucose and insulin metabolism using a multi-modal machine learning approach
- Josefin Henninger
- , Björn Eliasson
- & Aidin Rawshani
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| Open AccessMetagenomic characterization of swine slurry in a North American swine farm operation
- Akshaya Ramesh
- , Emily S. Bailey
- & Gregory C. Gray
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| Open AccessEvidence of new intragenic HBB haplotypes model for the prediction of beta-thalassemia in the Malaysian population
- Nur-Aisyah Aziz
- , Wan-Rohani Wan Taib
- & Hishamshah Ibrahim
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| Open AccessComparison of early F-18 Florbetaben PET/CT to Tc-99m ECD SPECT using voxel, regional, and network analysis
- Soo Jin Kwon
- , Seunggyun Ha
- & Joong-Seok Kim
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| Open AccessCombined genetic and chemical screens indicate protective potential for EGFR inhibition to cardiomyocytes under hypoxia
- Juho Heliste
- , Anne Jokilammi
- & Klaus Elenius
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| Open AccessICAM-1-carrying targeted nano contrast agent for evaluating inflammatory injury in rabbits with atherosclerosis
- Ping Li
- , Lin Jin
- & Rong Yang
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| Open AccessRole of interferon regulatory factor 7 in corneal endothelial cells after HSV-1 infection
- Fumie Ohtani
- , Dai Miyazaki
- & Yoshitsugu Inoue
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| Open AccessLiquid biopsy uncovers distinct patterns of DNA methylation and copy number changes in NSCLC patients with different EGFR-TKI resistant mutations
- Hoai-Nghia Nguyen
- , Ngoc-Phuong Thi Cao
- & Le Son Tran
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| Open AccessTherapeutic efficacy of macrolides in management of patients with mild COVID-19
- Alaa Rashad
- , Asmaa Nafady
- & Aida A. Abdelmaksoud
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| Open AccessCo-infections observed in SARS-CoV-2 positive patients using a rapid diagnostic test
- Carla Fontana
- , Marco Favaro
- & Anna Altieri
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| Open AccessEffect of black ginseng and silkworm supplementation on obesity, the transcriptome, and the gut microbiome of diet-induced overweight dogs
- Miey Park
- , Ki Hyun Kim
- & Hae-Jeung Lee
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| Open AccessATF6 is required for efficient rhodopsin clearance and retinal homeostasis in the P23H rho retinitis pigmentosa mouse model
- Eun-Jin Lee
- , Priscilla Chan
- & Jonathan H. Lin
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| Open AccessMetformin attenuates renal tubulointerstitial fibrosis via upgrading autophagy in the early stage of diabetic nephropathy
- Fengzhen Wang
- , Haihan Sun
- & Dong Sun
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| Open AccessClinical validation of optimised RT-LAMP for the diagnosis of SARS-CoV-2 infection
- Boon Lim
- , Jeremy Ratcliff
- & Monique I. Andersson
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| Open AccessEffects of selective EP2 receptor agonist, omidenepag, on trabecular meshwork cells, Schlemm’s canal endothelial cells and ciliary muscle contraction
- Natsuko Nakamura
- , Megumi Honjo
- & Makoto Aihara
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| Open AccessEnhanced genome editing efficiency of CRISPR PLUS: Cas9 chimeric fusion proteins
- Jongjin Park
- , Jiyoung Yoon
- & Sunghwa Choe
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| Open AccessElevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans
- Fanny M. Elahi
- , Danielle Harvey
- & Edward J. Goetzl
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| Open AccessMinimally invasive quantification of cerebral P2X7R occupancy using dynamic [18F]JNJ-64413739 PET and MRA-driven image derived input function
- Nathalie Mertens
- , Mark E. Schmidt
- & Michel Koole
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| Open AccessBenzalkonium chloride-induced myofibroblastic transdifferentiation of Tenon’s capsule fibroblasts is inhibited by coculture with corneal epithelial cells or by interleukin-10
- Chiemi Yamashiro
- , Kazuhiro Tokuda
- & Kazuhiro Kimura
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| Open AccessAlterations in plasma hyaluronic acid in patients with clinically stable COPD versus (non)smoking controls
- Kiki Waeijen-Smit
- , Niki L. Reynaert
- & Frits M. E. Franssen
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| Open AccessTranscriptomic profile of cationic channels in human pulmonary arterial hypertension
- Francisco Perez-Vizcaino
- , Angel Cogolludo
- & Gema Mondejar-Parreño
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| Open AccessThe COL-4A1 polypeptide destroy endothelial cells through the TGF-β/PI3K/AKT pathway
- Ting Li
- , Zhonghui Ling
- & Hongjuan Ding
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| Open AccessTranscriptomic landscape of blood platelets in healthy donors
- Anna Supernat
- , Marta Popęda
- & Anna J. Żaczek
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| Open AccessProtective effect of glycyrrhizin, a direct HMGB1 inhibitor, on post-contrast acute kidney injury
- Hyewon Oh
- , Arom Choi
- & Yong Eun Chung
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| Open AccessSirtuin 5 depletion impairs mitochondrial function in human proximal tubular epithelial cells
- Timo N. Haschler
- , Harry Horsley
- & Jill T. Norman
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| Open AccessSomatic cell hemoglobin modulates nitrogen oxide metabolism in the human airway epithelium
- Nadzeya Marozkina
- , Laura Smith
- & Benjamin Gaston
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| Open AccessGene expression profile of the murine ischemic retina and its response to Aflibercept (VEGF-Trap)
- Jesús Eduardo Rojo Arias
- & József Jászai
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| Open AccessPositron emission tomography imaging with 89Zr-labeled anti-CD8 cys-diabody reveals CD8+ cell infiltration during oncolytic virus therapy in a glioma murine model
- Benjamin B. Kasten
- , Hailey A. Houson
- & Anna G. Sorace
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| Open AccessIdentification of pathological transcription in autosomal dominant polycystic kidney disease epithelia
- Sebastian Friedrich
- , Hannah Müller
- & Alexis Hofherr
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| Open AccessMetabolic reprogramming in chondrocytes to promote mitochondrial respiration reduces downstream features of osteoarthritis
- Yoshifumi Ohashi
- , Nobunori Takahashi
- & Shiro Imagama
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| Open AccessRapid detection of phenotypes Bombay sedel and nonsecretor rs200157007 SNP (302C > T) by real-time PCR-based methods
- Mikiko Soejima
- & Yoshiro Koda
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| Open AccessCircular noncoding RNA hsa_circ_0005986 as a prognostic biomarker for hepatocellular carcinoma
- Gyeonghwa Kim
- , Ja Ryung Han
- & Keun Hur
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| Open AccessKinetics and seroprevalence of SARS-CoV-2 antibodies: a comparison of 3 different assays
- Elisabeth Kahre
- , Lukas Galow
- & Jakob P. Armann
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| Open AccessInhibition of the canonical Wnt signaling pathway by a β-catenin/CBP inhibitor prevents heart failure by ameliorating cardiac hypertrophy and fibrosis
- Thanachai Methatham
- , Shota Tomida
- & Kenichi Aizawa
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| Open AccessSHH-N non-canonically sustains androgen receptor activity in androgen-independent prostate cancer cells
- Diana Trnski
- , Maja Sabol
- & Petar Ozretić
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| Open AccessIn vitro evidence for the involvement of H2S pathway in the effect of clodronate during inflammatory response
- Rosangela Montanaro
- , Alessio D’Addona
- & Vincenzo Brancaleone
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| Open AccessGarlic (Allium sativum)-derived SEVs inhibit cancer cell proliferation and induce caspase mediated apoptosis
- İrem Özkan
- , Polen Koçak
- & Fikrettin Şahin
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| Open AccessMulti-omics integration of methyltransferase-like protein family reveals clinical outcomes and functional signatures in human cancer
- Ion John Campeanu
- , Yuanyuan Jiang
- & Zeng-Quan Yang
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| Open AccessChanges in abdominal subcutaneous adipose tissue phenotype following menopause is associated with increased visceral fat mass
- Julie Abildgaard
- , Thorkil Ploug
- & Birgitte Lindegaard
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| Open AccessPeptide VSAK maintains tissue glucose uptake and attenuates pro-inflammatory responses caused by LPS in an experimental model of the systemic inflammatory response syndrome: a PET study
- Ismael Luna-Reyes
- , Eréndira G. Pérez-Hernández
- & Jaime Mas-Oliva
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| Open AccessDifferences between antioxidant defense parameters and specific trace element concentrations in healthy, benign, and malignant brain tissues
- Slavica Borković-Mitić
- , Aleksandar Stojsavljević
- & Slađan Pavlović
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| Open AccessNo effect of deleted in malignant brain tumors 1 deficiency on chemotherapy induced murine intestinal mucositis
- Anders B. Nexoe
- , Andreas A. Pedersen
- & Mathias Rathe
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| Open AccessMeta-regression of randomized control trials with antithrombotics: weak correlation between net clinical benefit and all cause-mortality
- Roubi Kilo
- , Silvy Laporte
- & Jean-Christophe Lega