Featured
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Perspective |
Challenges and opportunities in achieving the full potential of droplet interface bilayers
Droplet interface bilayers (DIBs) are a type of artificial bilayer that can act as cell membrane mimics. This Perspective surveys how DIBs can be used to mimic key cellular features (such as bilayer asymmetry) and processes (such as drug movement), and discusses challenges that need to be overcome to enable DIBs to reach their full potential as biomimetic model membranes.
- Elanna B. Stephenson
- , Jaime L. Korner
- & Katherine S. Elvira
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Article |
Multi-responsive hydrogel structures from patterned droplet networks
Responsive hydrogels are of interest for a range of potential applications, including microscale soft robotic and biomedical devices. Now, a versatile fabrication approach has been developed to prepare patterned, multi-material and multi-responsive hydrogels. Pre-gel droplets are connected through lipid bilayers in predetermined architectures and photopolymerized to yield continuous hydrogel structures that respond to a variety of stimuli.
- Florence G. Downs
- , David J. Lunn
- & Hagan Bayley
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Article |
Placing and shaping liposomes with reconfigurable DNA nanocages
Controlling liposome shape, arrangement and dynamics is important for biophysical studies and synthetic biology applications. Now, using a family of reconfigurable DNA nanocages as templates, spherical, tubular, toroidal and helical liposomes with predefined geometry have been produced. DNA-guided membrane fusion and bending is also demonstrated.
- Zhao Zhang
- , Yang Yang
- & Chenxiang Lin