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| Open AccessMitogen activated protein kinase phosphatase 5 alleviates liver ischemia–reperfusion injury by inhibiting TAK1/JNK/p38 pathway
- Qiwen Yu
- , Sanyang Chen
- & Shuijun Zhang
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| Open AccessASC- and caspase-1-deficient C57BL/6 mice do not develop demyelinating disease after infection with Theiler’s murine encephalomyelitis virus
- Dandan Li
- , Melanie Bühler
- & Ingo Gerhauser
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| Open AccessAnti-inflammatory effects of CBD in human microglial cell line infected with HIV-1
- Adriana Yndart Arias
- , Nagesh Kolishetti
- & Madhavan Nair
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| Open AccessIL-37 alleviates Coxsackievirus B3-induced viral myocarditis via inhibiting NLRP3 inflammasome-mediated pyroptosis
- Lin Sun
- , Haitao Yuan
- & Gang Zhao
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| Open AccessPinocembrin suppresses oxidized low-density lipoprotein-triggered NLRP3 inflammasome/GSDMD-mediated endothelial cell pyroptosis through an Nrf2-dependent signaling pathway
- Tong Wang
- , Hua Tian
- & Shijun Wang
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| Open AccessThe PRY/SPRY domain of pyrin/TRIM20 interacts with β2-microglobulin to promote inflammasome formation
- Sei Samukawa
- , Ryusuke Yoshimi
- & Hideaki Nakajima
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| Open AccessDeletion of RAGE fails to prevent hepatosteatosis in obese mice due to impairment of other AGEs receptors and detoxifying systems
- Kristiaan Wouters
- , Alessia S. Cento
- & Raffaella Mastrocola
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Article
| Open AccessAn epigenetic GPI anchor defect impairs TLR4 signaling in the B cell transdifferentiation model for primary human monocytes BLaER1
- Julia Wegner
- , Thomas Zillinger
- & Martin Schlee
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| Open AccessIbrutinib does not prevent kidney fibrosis following acute and chronic injury
- Julie Belliere
- , Audrey Casemayou
- & Stanislas Faguer
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| Open AccessRiboflavin, vitamin B2, attenuates NLRP3, NLRC4, AIM2, and non-canonical inflammasomes by the inhibition of caspase-1 activity
- Huijeong Ahn
- & Geun-Shik Lee
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| Open AccessSENP7 knockdown inhibited pyroptosis and NF-κB/NLRP3 inflammasome pathway activation in Raw 264.7 cells
- Xun Li
- , Fangzhou Jiao
- & Zuojiong Gong
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| Open AccessCytotoxic effects of dental prosthesis grinding dust on RAW264.7 cells
- Wei Wang
- , Tianshu Li
- & Yuhe Zhu
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| Open AccessKefir peptides alleviate high-fat diet-induced atherosclerosis by attenuating macrophage accumulation and oxidative stress in ApoE knockout mice
- Min-Che Tung
- , Ying-Wei Lan
- & Chuan-Mu Chen
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| Open AccessRelevance of Caspase-1 and Nlrp3 Inflammasome on Inflammatory Bone Resorption in A Murine Model of Periodontitis
- Fernanda R G. Rocha
- , Andrea E. Delitto
- & Carlos Rossa Junior
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| Open AccessIn-vitro analysis of free radical scavenging activities and suppression of LPS-induced ROS production in macrophage cells by Solanum sisymbriifolium extracts
- Garland K. More
- & Raymond T. Makola
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Article
| Open AccessVisfatin/eNampt induces endothelial dysfunction in vivo: a role for Toll-Like Receptor 4 and NLRP3 inflammasome
- Tania Romacho
- , Inés Valencia
- & Carlos F. Sánchez-Ferrer
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| Open AccessSpirulina maxima extract prevents activation of the NLRP3 inflammasome by inhibiting ERK signaling
- Sungwoo Chei
- , Hyun-Ji Oh
- & Boo-Yong Lee
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Article
| Open AccessP2X7 Receptor Stimulation Is Not Required for Oxalate Crystal-Induced Kidney Injury
- Hannah L. Luz
- , Martin Reichel
- & Felix Knauf
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| Open AccessFebuxostat, a Xanthine Oxidoreductase Inhibitor, Decreases NLRP3-dependent Inflammation in Macrophages by Activating the Purine Salvage Pathway and Restoring Cellular Bioenergetics
- Johji Nomura
- , Tsunefumi Kobayashi
- & Nathalie Busso
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| Open AccessVU0155069 inhibits inflammasome activation independent of phospholipase D1 activity
- Sung Kyun Lee
- , Ye Seon Kim
- & Yoe-Sik Bae
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Article
| Open AccessNlrp1b1 negatively modulates obesity-induced inflammation by promoting IL-18 production
- Jonathan Salazar-León
- , Ana Laura Valdez-Hernández
- & Gustavo Pedraza-Alva
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| Open AccessInhibition of NLRP3 inflammasome in tumor microenvironment leads to suppression of metastatic potential of cancer cells
- Hye Eun Lee
- , Jin Young Lee
- & Joo Young Lee
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| Open AccessDifferential Immune Activation in Fetal Macrophage Populations
- Omar Lakhdari
- , Asami Yamamura
- & Lawrence S. Prince
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| Open AccessVibrio cholerae derived outer membrane vesicles modulate the inflammatory response of human intestinal epithelial cells by inducing microRNA-146a
- Aziz Bitar
- , Kyaw Min Aung
- & Marie-Louise Hammarström
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| Open AccessAmyloid β-dependent mitochondrial toxicity in mouse microglia requires P2X7 receptor expression and is prevented by nimodipine
- Paola Chiozzi
- , Alba Clara Sarti
- & Francesco Di Virgilio
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| Open AccessEarly endosome autoantigen 1 regulates IL-1β release upon caspase-1 activation independently of gasdermin D membrane permeabilization
- Alberto Baroja-Mazo
- , Vincent Compan
- & Pablo Pelegrín
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| Open AccessGlucosamine inhibits IL-1β expression by preserving mitochondrial integrity and disrupting assembly of the NLRP3 inflammasome
- Hsiao-Wen Chiu
- , Lan-Hui Li
- & Kuo-Feng Hua
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| Open AccessInhibition of NLRP3 inflammasome activation by cell-permeable stapled peptides
- Arumay Pal
- , Kurt Neo
- & Alessandra Mortellaro
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Article
| Open AccessThe NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1β-dependent manner in macrophages
- Orla M. Finucane
- , Jamie Sugrue
- & Marina A. Lynch
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| Open AccessBehçet’s disease and genetic interactions between HLA-B*51 and variants in genes of autoinflammatory syndromes
- Sergio Burillo-Sanz
- , Marco-Antonio Montes-Cano
- & María Francisca González-Escribano
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| Open AccessCaspase-4 disaggregates lipopolysaccharide micelles via LPS-CARD interaction
- Jinsu An
- , Seong Ho Kim
- & Hak Suk Chung
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Article
| Open AccessMercury and arsenic attenuate canonical and non-canonical NLRP3 inflammasome activation
- Huijeong Ahn
- , Jeongeun Kim
- & Geun-Shik Lee
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Article
| Open AccessDeath-associated protein kinase 1 mediates interleukin-1β production through regulating inlfammasome activation in Bv2 microglial cells and mice
- Limin Song
- , Lei Pei
- & Shanglong Yao
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| Open AccessAssociation of Inflammatory Responses and ECM Disorganization with HMGB1 Upregulation and NLRP3 Inflammasome Activation in the Injured Rotator Cuff Tendon
- Finosh G. Thankam
- , Zachary K. Roesch
- & Devendra K. Agrawal
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| Open AccessMCC950, a specific small molecule inhibitor of NLRP3 inflammasome attenuates colonic inflammation in spontaneous colitis mice
- Agampodi Promoda Perera
- , Ruchira Fernando
- & Rajaraman Eri
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| Open AccessHsp90 inhibition as a means to inhibit activation of the NLRP3 inflammasome
- Niina Piippo
- , Eveliina Korhonen
- & Anu Kauppinen
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Article
| Open AccessDevelopment of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses
- Elena Redondo-Castro
- , Dorte Faust
- & David Brough
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Article
| Open AccessInhibitory effects of superoxide dismutase 3 on Propionibacterium acnes-induced skin inflammation
- Cuong Thach Nguyen
- , Shyam Kishor Sah
- & Tae-Yoon Kim
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Article
| Open AccessMesenchymal stromal cells inhibit NLRP3 inflammasome activation in a model of Coxsackievirus B3-induced inflammatory cardiomyopathy
- Kapka Miteva
- , Kathleen Pappritz
- & Sophie Van Linthout
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Article
| Open AccessOmega-3 docosahexaenoic acid induces pyroptosis cell death in triple-negative breast cancer cells
- Nathalia Pizato
- , Beatriz Christina Luzete
- & Kelly Grace Magalhães
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Article
| Open AccessNLRP3 inflammasome is a key player in human vulvovaginal disease caused by
Candida albicans - Elena Roselletti
- , Stefano Perito
- & Anna Vecchiarelli
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| Open AccessEpidermal cornification is preceded by the expression of a keratinocyte-specific set of pyroptosis-related genes
- Julia Lachner
- , Veronika Mlitz
- & Leopold Eckhart
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| Open AccessBOT-4-one attenuates NLRP3 inflammasome activation: NLRP3 alkylation leading to the regulation of its ATPase activity and ubiquitination
- Do-Wan Shim
- , Woo-Young Shin
- & Kwang-Ho Lee
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Article
| Open AccessMethylene blue inhibits NLRP3, NLRC4, AIM2, and non-canonical inflammasome activation
- Huijeong Ahn
- , Seung Goo Kang
- & Geun-Shik Lee
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| Open AccessNLRP3 inflammasome activation results in liver inflammation and fibrosis in mice infected with Schistosoma japonicum in a Syk-dependent manner
- Ya-Qi Lu
- , Shan Zhong
- & Wang-Xian Tang
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| Open AccessSalmonella typhimurium-induced IL-1 release from primary human monocytes requires NLRP3 and can occur in the absence of pyroptosis
- Catherine E. Diamond
- , Keith Weng Kit Leong
- & Alessandra Mortellaro
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| Open AccessBlockade of high-mobility group box 1 attenuates intestinal mucosal barrier dysfunction in experimental acute pancreatitis
- Xia Chen
- , Hong-Xian Zhao
- & Xiang-Yu Zhou
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Article
| Open AccessBone matrix components activate the NLRP3 inflammasome and promote osteoclast differentiation
- Yael Alippe
- , Chun Wang
- & Gabriel Mbalaviele
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| Open AccessFree immunoglobulin light chain (FLC) promotes murine colitis and colitis-associated colon carcinogenesis by activating the inflammasome
- Junfan Ma
- , Dongyang Jiang
- & Xiaoyan Qiu