Genotype

Definition

The genotype is the genetic makeup of a cell, organism or individual with reference to a particular characteristic. In diploid or polyploid individuals, it refers to what combination of alleles the individual carries.

Latest Research and Reviews

  • Research | | open

    Male pattern baldness (MBP) is a complex trait that has genetic associations. Here, Pirastu and colleagues perform a genome-wide association study to show 71 susceptibility loci associated with MBP — 30 of which are novel — and that these loci can explain 38% of heritability.

    • Nicola Pirastu
    • , Peter K. Joshi
    • , Paul S. de Vries
    • , Marilyn C. Cornelis
    • , Paul M. McKeigue
    • , NaNa Keum
    • , Nora Franceschini
    • , Marco Colombo
    • , Edward L. Giovannucci
    • , Athina Spiliopoulou
    • , Lude Franke
    • , Kari E. North
    • , Peter Kraft
    • , Alanna C. Morrison
    • , Tõnu Esko
    •  & James F. Wilson
  • Research | | open

    • Anna Szécsényi-Nagy
    • , Christina Roth
    • , Guido Brandt
    • , Cristina Rihuete-Herrada
    • , Cristina Tejedor-Rodríguez
    • , Petra Held
    • , Íñigo García-Martínez-de-Lagrán
    • , Héctor Arcusa Magallón
    • , Stephanie Zesch
    • , Corina Knipper
    • , Eszter Bánffy
    • , Susanne Friederich
    • , Harald Meller
    • , Primitiva Bueno Ramírez
    • , Rosa Barroso Bermejo
    • , Rodrigo de Balbín Behrmann
    • , Ana M. Herrero-Corral
    • , Raúl Flores Fernández
    • , Carmen Alonso Fernández
    • , Javier Jiménez Echevarria
    • , Laura Rindlisbacher
    • , Camila Oliart
    • , María-Inés Fregeiro
    • , Ignacio Soriano
    • , Oriol Vicente
    • , Rafael Micó
    • , Vicente Lull
    • , Jorge Soler Díaz
    • , Juan Antonio López Padilla
    • , Consuelo Roca de Togores Muñoz
    • , Mauro S. Hernández Pérez
    • , Francisco Javier Jover Maestre
    • , Joaquín Lomba Maurandi
    • , Azucena Avilés Fernández
    • , Katina T. Lillios
    • , Ana Maria Silva
    • , Miguel Magalhães Ramalho
    • , Luiz Miguel Oosterbeek
    • , Claudia Cunha
    • , Anna J. Waterman
    • , Jordi Roig Buxó
    • , Andrés Martínez
    • , Juana Ponce Martínez
    • , Mark Hunt Ortiz
    • , Juan Carlos Mejías-García
    • , Juan Carlos Pecero Espín
    • , Rosario Cruz-Auñón Briones
    • , Tiago Tomé
    • , Eduardo Carmona Ballestero
    • , João Luís Cardoso
    • , Ana Cristina Araújo
    • , Corina Liesau von Lettow-Vorbeck
    • , Concepción Blasco Bosqued
    • , Patricia Ríos Mendoza
    • , Ana Pujante
    • , José I. Royo-Guillén
    • , Marco Aurelio Esquembre Beviá
    • , Victor Manuel Dos Santos Goncalves
    • , Rui Parreira
    • , Elena Morán Hernández
    • , Elena Méndez Izquierdo
    • , Jorge Vega y Miguel
    • , Roberto Menduiña García
    • , Victoria Martínez Calvo
    • , Oscar López Jiménez
    • , Johannes Krause
    • , Sandra L. Pichler
    • , Rafael Garrido-Pena
    • , Michael Kunst
    • , Roberto Risch
    • , Manuel A. Rojo-Guerra
    • , Wolfgang Haak
    •  & Kurt W. Alt
  • Reviews |

    Populations of African descent are at the forefront of the worldwide epidemic of type 2 diabetes mellitus (T2DM). Here, Anne Sumner and colleagues discuss issues related to the diagnosis and prevention of T2DM in these populations, including screening test efficacy, prevention strategies and the relative paucity of genomic data.

    • Jean N. Utumatwishima
    • , Stephanie T. Chung
    • , Amy R. Bentley
    • , Margaret Udahogora
    •  & Anne E. Sumner

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