Epigenetics articles within Nature Materials

Featured

• Feature | 23 May 2018

  Adoptive T cell cancer therapy

  Tumour heterogeneity and off-target toxicity are current challenges of cancer immunotherapy. Karine Dzhandzhugazyan, Per Guldberg and Alexei Kirkin discuss how epigenetic induction of tumour antigens in antigen-presenting cells may form the basis for multi-target therapies.

  • Karine N. Dzhandzhugazyan
  • , Per Guldberg
  •  & Alexei F. Kirkin

• News & Views | 21 November 2013

  Into the groove

  Adult cells can be routinely reprogrammed into pluripotent stem cells by chemical and genetic means, such as the expression of a cocktail of exogenous transcription factors. It is now shown that growing cells on substrates with aligned features such as microgrooves can enhance this process.

  • Yan Xu
  • , Longqi Liu
  •  & Miguel A. Esteban