Molecular biology articles within Nature Materials

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• Comment | 19 May 2020

  Materials science approaches in the development of broad-spectrum antiviral therapies

  The COVID-19 pandemic has reignited efforts to develop materials science innovations aimed at stopping viral infections. One of the greatest opportunities lies in developing broad-spectrum antiviral technologies that work against many viruses, which could be the key to thwarting outbreaks in the future.

  • Nam Joon Cho
  •  & Jeffrey S. Glenn

• Article | 15 October 2018

  Injectable tissue integrating networks from recombinant polypeptides with tunable order

  A protein-based material with temperature-modulated mechanical properties and function is achieved by the rational incorporation of structural ordering and disordering elements into its polypeptide sequence.

  • Stefan Roberts
  • , Tyler S. Harmon
  •  & Ashutosh Chilkoti

• Feature | 23 May 2018

  Adoptive T cell cancer therapy

  Tumour heterogeneity and off-target toxicity are current challenges of cancer immunotherapy. Karine Dzhandzhugazyan, Per Guldberg and Alexei Kirkin discuss how epigenetic induction of tumour antigens in antigen-presenting cells may form the basis for multi-target therapies.

  • Karine N. Dzhandzhugazyan
  • , Per Guldberg
  •  & Alexei F. Kirkin

• Research Highlights | 21 November 2013

  Rapid unfolding

  • Pep Pàmies

• News & Views | 21 November 2013

  Into the groove

  Adult cells can be routinely reprogrammed into pluripotent stem cells by chemical and genetic means, such as the expression of a cocktail of exogenous transcription factors. It is now shown that growing cells on substrates with aligned features such as microgrooves can enhance this process.

  • Yan Xu
  • , Longqi Liu
  •  & Miguel A. Esteban

• Research Highlights | 23 September 2011

  Replication and reproduction

  • Pep Pàmies

• Article | 24 January 2010

  Multimeric small interfering ribonucleic acid for highly efficient sequence-specific gene silencing

  Small interfering ribonucleic acid (siRNA) is used to silence genes and treat conditions such as human immunodeficiency virus. Safe and efficient delivery, however, is proving problematic. A new class of biologically active siRNA polyelectrolyte complexes based on chemically self-crosslinked siRNA is presented, which shows greatly enhanced gene-silencing efficiencies in vitro and in vivo without significantly eliciting an immune response.

  • Hyejung Mok
  • , Soo Hyeon Lee
  •  & Tae Gwan Park