Cervical cancer articles within Nature

Featured

  • Article
    | Open Access

    This paper describes molecular subtypes of cervical cancers, including squamous cell carcinoma and adenocarcinoma clusters defined by HPV status and molecular features, and distinct molecular pathways that are activated in cervical carcinomas caused by different somatic alterations and HPV types.

    • Robert D. Burk
    • , Zigui Chen
    •  & David Mutch

  • Letter |

    Whole-exome sequencing and analysis of 115 cervical carcinoma–normal paired samples, in addition to transcriptome and whole-genome sequencing for a subset of these tumours, reveal novel genes mutated at significant levels within this cohort and provide evidence that HPV integration is a common mechanism for target gene overexpression; results also compare mutational landscapes between squamous cell carcinomas and adenocarcinomas.

    • Akinyemi I. Ojesina
    • , Lee Lichtenstein
    •  & Matthew Meyerson

  • Outlook |

    Human papillomavirus (HPV) has become synonymous with cervical cancer, but its actual footprint is much bigger, by James Mitchell Crow.

    • James Mitchell Crow

  • Outlook |

    Pap tests have been a mainstay of cervical cancer screening, but new tests, vaccines and knowledge might be changing that, including when and how frequently to test.

    • Courtney Humphries

  • Outlook |

    Two vaccines seem to be so effective in preventing HPV infection that mass vaccination has been introduced for girls. But will long-term studies show falls in cervical cancer?

    • Julie Clayton

  • Outlook |

    Linking specific types of HPV with cervical cancer and developing effective vaccines against should be celebrated. But there are gaps in our understanding of these viruses and how they cause disease.

    • Laura Vargas-Parada

  • Outlook |

    A Nobel prizewinner for pinning cervical cancer on human papillomavirus, Harald zur Hausen still investigates viruses. Nature Outlook talks to the medical doctor–turned–virologist about other possible culprits.

    • Harald zur Hausen

  • Outlook |

    Vaccines on the market aren't practical for the developing world — where cervical cancer hits hardest — but researchers are trying to make ones that are.

    • Katharine Sanderson

  • Outlook |

    Sub-Saharan countries lag behind in screening and treatment for human papillomavirus. But national efforts and the introduction of low-tech methods could change that.

    • Michael Eisenstein

Browse broader subjects

Browse Cervical cancer across other nature.com journals