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Cell growth usually refers to cell proliferation, the increase in cell numbers that occurs through repeated cell division. Cell growth can also refer to the enlargement of cell volume, which can take place in the absence of cell division.
It is remarkable how robustly a bacterial species can maintain its preferred size. In this Review, Willis and Huang explore classic and current knowledge of the mechanisms that coordinate bacterial cell size with essential growth and cell cycle processes.
The Hippo pathway responds to environmental factors including nutrient availability, cell density and substrate stiffness to regulate organ size. This pathway is now shown to also regulate antiviral defence by modulating the TBK1-mediated control of interferon production.