Research Highlight |
Featured
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Tools in Brief |
Electrophysiology in intact Caenorhabditis elegans
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Article |
Stable long-term chronic brain mapping at the single-neuron level
Flexible mesh electronics facilitate stable long-term recordings of the same single neurons in mouse brains over months, enabling chronic recordings in behaving animals and longitudinal studies to resolve aging-dependent changes in neural activity.
- Tian-Ming Fu
- , Guosong Hong
- & Charles M Lieber
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Tools in Brief |
Flexible and minimally invasive nanowires
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News & Views |
Another transistor-based revolution: on-chip qPCR
More than 40 years after the invention of semiconductor pH microtransducers known as ISFETs, this transistor-based technology may revolutionize quantitative PCR.
- Carlotta Guiducci
- & Fabio M Spiga
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News & Views |
Close encounters: integrating nanopores and CMOS amplifiers for single-molecule detection
Using semiconductor processing to construct integrated circuits that reside close to nanopores, researchers demonstrate high-bandwidth, low-noise measurements of DNA translocation through solid-state nanopores.
- John S Oliver
- & Valentin Dimitrov