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| Open AccessSynthesis of a highly water-soluble acacetin prodrug for treating experimental atrial fibrillation in beagle dogs
- Hui Liu
- , Ya-Jing Wang
- & Gui-Rong Li
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| Open AccessGeneration of exogenous germ cells in the ovaries of sterile NANOS3-null beef cattle
- Atsushi Ideta
- , Shiro Yamashita
- & Yutaka Sendai
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| Open AccessIdentification and characterization of rabbit ROSA26 for gene knock-in and stable reporter gene expression
- Dongshan Yang
- , Jun Song
- & Y. Eugene Chen
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| Open AccessIncreased and prolonged human norovirus infection in RAG2/IL2RG deficient gnotobiotic pigs with severe combined immunodeficiency
- Shaohua Lei
- , Junghyun Ryu
- & Lijuan Yuan
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| Open AccessExpression of Active Fluorophore Proteins in the Milk of Transgenic Pigs Bypassing the Secretory Pathway
- Ayan Mukherjee
- , Wiebke Garrels
- & Wilfried A. Kues
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| Open AccessGeneration of heterozygous fibrillin-1 mutant cloned pigs from genome-edited foetal fibroblasts
- Kazuhiro Umeyama
- , Kota Watanabe
- & Morio Matsumoto
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| Open AccessThe first description of complete invertebrate arginine metabolism pathways implies dose-dependent pathogen regulation in Apostichopus japonicus
- Shao Yina
- , Li Chenghua
- & Lv Zhimeng
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| Open AccessRestoration of normal embryogenesis by mitochondrial supplementation in pig oocytes exhibiting mitochondrial DNA deficiency
- Gael L. M. Cagnone
- , Te-Sha Tsai
- & Justin C. St. John
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| Open AccessTargeted disruption of sp7 and myostatin with CRISPR-Cas9 results in severe bone defects and more muscular cells in common carp
- Zhaomin Zhong
- , Pengfei Niu
- & Han Wang
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| Open AccessLarge-scale production of functional human lysozyme from marker-free transgenic cloned cows
- Dan Lu
- , Shen Liu
- & Ning Li
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| Open AccessSpecific LED-based red light photo-stimulation procedures improve overall sperm function and reproductive performance of boar ejaculates
- Marc Yeste
- , Francesc Codony
- & Joan E. Rodríguez-Gil
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| Open AccessCRISPR/Cas9-mediated GJA8 knockout in rabbits recapitulates human congenital cataracts
- Lin Yuan
- , Tingting Sui
- & Liangxue Lai
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| Open AccessOne-step Multiplex Transgenesis via Sleeping Beauty Transposition in Cattle
- Wiebke Garrels
- , Thirumala R. Talluri
- & Wilfried A. Kues
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| Open AccessThalidomide-induced limb abnormalities in a humanized CYP3A mouse model
- Yasuhiro Kazuki
- , Masaharu Akita
- & Mitsuo Oshimura
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| Open AccessMammalian interspecies substitution of immune modulatory alleles by genome editing
- Simon G. Lillico
- , Chris Proudfoot
- & C. Bruce A. Whitelaw
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| Open AccessGeneration of TALE nickase-mediated gene-targeted cows expressing human serum albumin in mammary glands
- Yan Luo
- , Yongsheng Wang
- & Yong Zhang
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| Open AccessDevelopment of a conditional liver tumor model by mifepristone-inducible Cre recombination to control oncogenic krasV12 expression in transgenic zebrafish
- Anh Tuan Nguyen
- , Vivien Koh
- & Zhiyuan Gong
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| Open AccessHigh total antioxidant capacity of the porcine seminal plasma (SP-TAC) relates to sperm survival and fertility
- Isabel Barranco
- , Asta Tvarijonaviciute
- & Jordi Roca
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| Open AccessTALEN-mediated homologous recombination in Daphnia magna
- Takashi Nakanishi
- , Yasuhiko Kato
- & Hajime Watanabe
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| Open AccessEfficient Generation of Mice with Consistent Transgene Expression by FEEST
- Lei Gao
- , Yonghua Jiang
- & Liang Chen
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| Open AccessLarge-scale production of bioactive recombinant human acidic fibroblast growth factor in transgenic silkworm cocoons
- Feng Wang
- , Riyuan Wang
- & Qingyou Xia
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| Open AccessProduction of Human Albumin in Pigs Through CRISPR/Cas9-Mediated Knockin of Human cDNA into Swine Albumin Locus in the Zygotes
- Jin Peng
- , Yong Wang
- & Pumin Zhang
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| Open Access2A self-cleaving peptide-based multi-gene expression system in the silkworm Bombyx mori
- Yuancheng Wang
- , Feng Wang
- & Qingyou Xia
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| Open AccessA transgenic embryonic sexing system for the Australian sheep blow fly Lucilia cuprina
- Ying Yan
- & Maxwell J. Scott
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| Open AccessGeneration of hypoxanthine phosphoribosyltransferase gene knockout rabbits by homologous recombination and gene trapping through somatic cell nuclear transfer
- Mingru Yin
- , Weihua Jiang
- & Shangang Li
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| Open AccessProduction of reproductively sterile fish by a non-transgenic gene silencing technology
- Ten-Tsao Wong
- & Yonathan Zohar
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| Open AccessHyper sensitive protein detection by Tandem-HTRF reveals Cyclin D1 dynamics in adult mouse
- Alexandre Zampieri
- , Julien Champagne
- & Frédéric Bienvenu
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| Open AccessAdeno-associated-virus-mediated transduction of the mammary gland enables sustained production of recombinant proteins in milk
- Stefan Wagner
- , Rosemary Thresher
- & Götz Laible
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| Open AccessHighly efficient CRISPR/Cas9-mediated transgene knockin at the H11 locus in pigs
- Jinxue Ruan
- , Hegang Li
- & Kui Li
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| Open AccessDirect production of XYDMY− sex reversal female medaka (Oryzias latipes) by embryo microinjection of TALENs
- Daji Luo
- , Yun Liu
- & Wei Hu
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| Open AccessCRISPR/Cas9-based generation of knockdown mice by intronic insertion of artificial microRNA using longer single-stranded DNA
- Hiromi Miura
- , Channabasavaiah B Gurumurthy
- & Masato Ohtsuka
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| Open AccessFirst mitochondrial genome for the red crab (Charybdis feriata) with implication of phylogenomics and population genetics
- Hongyu Ma
- , Chunyan Ma
- & Lianjun Xia
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| Open AccessEfficient introgression of allelic variants by embryo-mediated editing of the bovine genome
- Jingwei Wei
- , Stefan Wagner
- & Götz Laible
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| Open AccessGONAD: Genome-editing via Oviductal Nucleic Acids Delivery system: a novel microinjection independent genome engineering method in mice
- Gou Takahashi
- , Channabasavaiah B Gurumurthy
- & Masato Ohtsuka
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| Open AccessA minimally invasive, lentiviral based method for the rapid and sustained genetic manipulation of renal tubules
- Judit Espana-Agusti
- , David A. Tuveson
- & Athena Matakidou
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| Open AccessNonsurgical deep uterine transfer of vitrified, in vivo-derived, porcine embryos is as effective as the default surgical approach
- Emilio A. Martinez
- , Cristina A Martinez
- & Cristina Cuello
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| Open AccessGene targeting by TALEN-induced homologous recombination in goats directs production of β-lactoglobulin-free, high-human lactoferrin milk
- Chenchen Cui
- , Yujie Song
- & Yong Zhang
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| Open AccessCRISPR-engineered mosaicism rapidly reveals that loss of Kcnj13 function in mice mimics human disease phenotypes
- Hua Zhong
- , Yiyun Chen
- & Graeme Mardon
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| Open AccessEfficient generation of gene-modified pigs via injection of zygote with Cas9/sgRNA
- Yong Wang
- , Yinan Du
- & Hong Wei
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| Open AccessAn injectable acoustic transmitter for juvenile salmon
- Z. D. Deng
- , T. J. Carlson
- & M. B. Eppard
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| Open AccessA controllable on-off strategy for the reproductive containment of fish
- Yunsheng Zhang
- , Ji Chen
- & Wei Hu
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| Open AccessAsymmetric parental genome engineering by Cas9 during mouse meiotic exit
- Toru Suzuki
- , Maki Asami
- & Anthony C. F. Perry
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| Open AccessEfficient bi-allelic gene knockout and site-specific knock-in mediated by TALENs in pigs
- Jing Yao
- , Jiaojiao Huang
- & Jianguo Zhao
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| Open AccessSimple knockout by electroporation of engineered endonucleases into intact rat embryos
- Takehito Kaneko
- , Tetsushi Sakuma
- & Tomoji Mashimo
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Article
| Open AccessProduction of recombinant human proinsulin in the milk of transgenic mice
- Xi Qian
- , Jana Kraft
- & Feng-Qi Zhao
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| Open AccessEfficient genetic manipulation of the NOD-Rag1-/-IL2RgammaC-null mouse by combining in vitro fertilization and CRISPR/Cas9 technology
- Feng Li
- , Dale O. Cowley
- & Lishan Su
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| Open AccessImproved site-specific recombinase-based method to produce selectable marker- and vector-backbone-free transgenic cells
- Yuan Yu
- , Qi Tong
- & Yong Zhang
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| Open AccessIdentification of germline transcriptional regulatory elements in Aedes aegypti
- Omar S. Akbari
- , Philippos A. Papathanos
- & Bruce A. Hay
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| Open AccessA non-surgical approach for male germ cell mediated gene transmission through transgenesis
- Abul Usmani
- , Nirmalya Ganguli
- & Subeer S. Majumdar