Acute inflammatory arthritis

Acute inflammatory arthritis is an umbrella term that describes a group of disorders characterized by joint inflammation involving the immune system and sudden, painful onset.

Latest Research and Reviews

  • Reviews |

    Hyperuricaemia is a risk factor for gout, and mouse models of this condition can help dissect the underlying regulatory mechanisms. However, these models come with both advantages and disadvantages, and interpreting and comparing data from these models can be challenging.

    • Jie Lu
    • , Nicola Dalbeth
    • , Huiyong Yin
    • , Changgui Li
    • , Tony R. Merriman
    •  & Wen-Hua Wei
  • Research | | open

    Loss of cartilage tissue is a hallmark of osteoarthritis. Here the authors show that BNTA, a small molecule identified in a chemical screen, promotes ECM generation in human osteoarthritic chondrocytes and cartilage explants, and suppresses pathology in a rat model of osteoarthritis.

    • Yuanyuan Shi
    • , Xiaoqing Hu
    • , Jin Cheng
    • , Xin Zhang
    • , Fengyuan Zhao
    • , Weili Shi
    • , Bo Ren
    • , Huilei Yu
    • , Peng Yang
    • , Zong Li
    • , Qiang Liu
    • , Zhenlong Liu
    • , Xiaoning Duan
    • , Xin Fu
    • , Jiying Zhang
    • , Jianquan Wang
    •  & Yingfang Ao
  • Research | | open

    Masahiro Nakatochi et al. report a genome-wide meta-analysis of serum uric acid levels in the Japanese population. They identify 36 loci, including eight previously unreported loci, suggesting key cellular processes that contribute to elevated serum uric acid levels, which can lead to gout.

    • Masahiro Nakatochi
    • , Masahiro Kanai
    • , Akiyoshi Nakayama
    • , Asahi Hishida
    • , Yusuke Kawamura
    • , Sahoko Ichihara
    • , Masato Akiyama
    • , Hiroaki Ikezaki
    • , Norihiro Furusyo
    • , Seiko Shimizu
    • , Ken Yamamoto
    • , Makoto Hirata
    • , Rieko Okada
    • , Sayo Kawai
    • , Makoto Kawaguchi
    • , Yuichiro Nishida
    • , Chisato Shimanoe
    • , Rie Ibusuki
    • , Toshiro Takezaki
    • , Mayuko Nakajima
    • , Mikiya Takao
    • , Etsuko Ozaki
    • , Daisuke Matsui
    • , Takeshi Nishiyama
    • , Sadao Suzuki
    • , Naoyuki Takashima
    • , Yoshikuni Kita
    • , Kaori Endoh
    • , Kiyonori Kuriki
    • , Hirokazu Uemura
    • , Kokichi Arisawa
    • , Isao Oze
    • , Keitaro Matsuo
    • , Yohko Nakamura
    • , Haruo Mikami
    • , Takashi Tamura
    • , Hiroshi Nakashima
    • , Takahiro Nakamura
    • , Norihiro Kato
    • , Koichi Matsuda
    • , Yoshinori Murakami
    • , Tatsuaki Matsubara
    • , Mariko Naito
    • , Michiaki Kubo
    • , Yoichiro Kamatani
    • , Nariyoshi Shinomiya
    • , Mitsuhiro Yokota
    • , Kenji Wakai
    • , Yukinori Okada
    •  & Hirotaka Matsuo
  • Research | | open

    • Wei-Cheng Tseng
    • , Yung-Tai Chen
    • , Yao-Ping Lin
    • , Shuo-Ming Ou
    • , Chih-Yu Yang
    • , Chi-Hung Lin
    • , Der-Cherng Tarng
    • , Der-Cherng Tarng
    • , Wei-Cheng Tseng
    • , Ming-Tsun Tsai
    • , Shuo-Ming Ou
    • , Chih-Yu Yang
    • , Yao-Ping Lin
    • , Yu-Hsin Chen
    • , Yi-Fang Chuang
    • , Liang-Kung Chen
    • , Kwua-Yun Wang
    • , Chia-Jen Shih
    • , Yung-Tai Chen
    • , Yi-Sheng Lin
    • , Szu-Chun Hung
    • , Ko-Lin Kuo
    • , Tung-Po Hung
    • , Fen-Hsiang Hu
    • , Nien-Jung Chen
    • , Yu-Chi Chen
    • , Chi-Hung Lin
    • , Tung-Hu Tsai
    • , Shie-Liang Hsieh
    • , Yau-Huei Wei
    • , Chih-Cheng Hsu
    • , Jia-Sin Liu
    • , Yu-Kang Chang
    •  & Ming-Han Chiang

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