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Determination of the pKa values of the γ-phosphate in p21ras mutants provides the first experimental evidence for substrate-assisted catalysis in the intrinsic GTPase reaction.
The crystal structure of the PurR-DNA complex reveals how α-helices can be used for minor groove recognition and provides a model for the Lad family of repressors.
A novel common fold observed in the structures of elongation factor G, DNA gyrase B and ribosomal protein S5 displays a rare topological feature suggesting the high probability of an evolutionary relationship
