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Histones push the envelope

Nature Structural & Molecular Biology volume 21, pages 651–652 (2014)Cite this article

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The development of new strategies to deplete maternal histone proteins in vivo and in vitro has led to the discovery of unexpected roles of histones in forming a functional nuclear envelope.

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Figure 1: New strategies for developing nucleosome-depleted model systems based upon the depletion of maternal histone proteins.

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Acknowledgements

P.J.S. is supported by the Damon Runyon Cancer Research Foundation as a Damon Runyon Fellow (DRG-2110-12). S.H. is supported as an Investigator of the Howard Hughes Medical Institute.

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Authors and Affiliations

  1. Peter J. Skene and Steven Henikoff are at the Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.,

    Peter J Skene & Steven Henikoff

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  1. Peter J Skene
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  2. Steven Henikoff
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Correspondence to Steven Henikoff.

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The authors declare no competing financial interests.

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Skene, P., Henikoff, S. Histones push the envelope. Nat Struct Mol Biol 21, 651–652 (2014). https://doi.org/10.1038/nsmb.2864

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