Volume 16 Issue 11, November 2020

Suboptimal medication adherence, a major problem among individuals with systemic lupus erythematosus, is often more pronounced among minority racial groups. As the roots of racial disparities in treatment adherence are beginning to be untangled, the need for multidisciplinary, multilevel approaches to tackle this complex problem is emerging.

Comorbidities are highly prevalent in patients with rheumatoid arthritis (RA), yet clinical care for such patients is often of inferior quality, even in rheumatology clinics. Suggestions for good clinical practice interventions from an expert panel aim to improve the quality of care for patients with RA who have associated comorbidities.

In this Review, the authors discuss how new approaches, including imaging, tissue analysis and omics technologies, could be applied to identify patients with a poor prognosis and to predict response to treatment, thus enabling precision medicine and improving outcomes in psoriatic disease.

The effects of sex steroids (oestrogens, androgens and progesterone) on immune responses contribute to the sex bias in autoimmune rheumatic diseases in complex ways. Targeting these effects could hold potential for treating patients with autoimmune rheumatic diseases.

Fibromyalgia is a complex and common condition characterized by chronic widespread pain and numerous other symptoms. This Review outlines different clinical aspects of fibromyalgia, including the burden, diagnosis and treatment of this condition, and discusses various hypotheses of fibromyalgia etiopathogenesis.