Browse Articles

In this Review, Ledvina and Whiteley highlight the key similarities between eukaryotic and bacterial innate immune systems, exploring conserved immune components and signalling strategies, as well as conserved mechanisms for pathogen restriction.

Wastewater genomic surveillance can transform global viral disease monitoring. This Genome Watch article explores the techniques, analytical pipelines and implications for public health.

In this study, Fu et al. show that Streptococcus anginosus promotes gastric tumorigenesis in mice.

In this Journal Club, Amelia Barber discusses a study revealing intraspecies heterogeneity in a fungal pathogen, prompting us to re-evaluate the notion of ‘reference’ strains.

In this study, Achberger et al. report that microbial communities of inactive hydrothermal deposits contribute to primary productivity in the deep sea.

This month’s Genome Watch discusses the application of spatial transcriptomics to investigate the arrangements of microbial communities and their effects on the host.

The study provides insights into how insects and their endosymbionts can manipulate plant defences.

This study shows that the distinct cellular organization across the depth of a biofilm is tightly regulated and has consequences for cell physiology and antibiotic tolerance.

Finding a cure for HIV-1 infection, once considered elusive, now represents a major priority for the global microbiology research community. In this article, Armani-Tourret, Lichterfeld and colleagues highlight recent advances in understanding immunological vulnerabilities of virally infected cells that persist lifelong and represent the major barrier to a cure.

In this Review, Rosenthal, Asua and Conrad summarize our current knowledge of artemisinin partial resistance and focus on the emergence of resistance in Africa, including its epidemiology and transmission dynamics, and mechanisms of resistance.

This study describes a signalling pathway involving the host receptor GPR35 and members of the gut microbiota, such as Parabacteroides distasonis, which regulates depressive-like behaviour.

This study reports that antibodies that target the fusion peptide on the HIV envelope provide protection to rhesus macaques against mucosal simian-HIV challenge.

This Genome Watch article highlights how studying pathogens in the context of their phylogenetic neighbours can provide insights into their evolution.

In this Review, Jones, Marken and Silver develop a conceptual framework for synthetic microbiology organized into three domains — factory, farm and field — to explore the utility of synthetic microbiology in addressing sustainability challenges, and examine several examples of microbial engineering applications relevant to each domain.

This study describes Bdellovibrio bacteriovorus trimeric fibre proteins with diverse adhesive tips that enable the identification of a broad range of prey.

In this study, Knödlseder et al. explore the potential of an engineered Cutibacterium acnes strain as a microbiome-based therapy for skin conditions.

In this Review, Thiel and colleagues summarize our emerging knowledge of the SARS-CoV-2 intracellular life cycle and the molecular functions of the viral proteins, as well as their interaction with the host cell.

In this Review, Roussin-Léveillée, Mackey and colleagues examine microorganism interaction with and manipulation of the plant apoplast. Effector-driven extracellular niche establishment is conceptualized as foundational to plant pathogenesis and frames the discussion of the complex interplay between pathogen virulence, host immunity and the physiological dynamics shaping plant–microorganism interactions.