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Latest Reviews

  • Review |

    Aspergillus fumigatus is an environmental fungus that can cause life-threatening disease. In this Review, van de Veerdonk and colleagues describe how A. fumigatus adapts to environmental change, mechanisms of host defence and our current knowledge of the interplay between the host immune response and the fungus.

    • Frank L. van de Veerdonk
    • , Mark S. Gresnigt
    • , Luigina Romani
    • , Mihai G. Netea
    •  & Jean-Paul Latgé
  • Review |

    Apicomplexa include important human pathogens and possess a unique cellular machinery that promotes gliding motility and is called the glideosome. In this Review, Soldati-Favre and colleagues discuss the principles that govern gliding motility, the characterization of the molecular machinery that comprises the glideosome, and its impact on parasite invasion and egress from infected cells.

    • Karine Frénal
    • , Jean-François Dubremetz
    • , Maryse Lebrun
    •  & Dominique Soldati-Favre
  • Review |

    Soil contains a vast diversity of microorganisms that can directly or indirectly modulate soil processes and terrestrial ecosystems. In this Review, Fierer summarizes the challenges in characterizing the composition and functions of the soil microbiome, and discusses key future research directions.

    • Noah Fierer
  • Review |

    It is remarkable how robustly a bacterial species can maintain its preferred size. In this Review, Willis and Huang explore classic and current knowledge of the mechanisms that coordinate bacterial cell size with essential growth and cell cycle processes.

    • Lisa Willis
    •  & Kerwyn Casey Huang
  • Review |

    The fungal kingdom contains many important plant pathogens, and some species show remarkable variation in genome size and architecture. In this Review, Möller and Stukenbrock summarize key examples from fungal plant pathogen genomics and discuss evolutionary processes in pathogenic fungi in the context of molecular evolution, population genetics and agriculture.

    • Mareike Möller
    •  & Eva H. Stukenbrock
  • Opinion |

    Risk assessment for the development of antibiotic resistance against a new drug candidate is of paramount importance in preclinical development. In this Opinion article, Sommer et al. propose a new preclinical paradigm for the prediction of antibiotic resistance.

    • Morten O. A. Sommer
    • , Christian Munck
    • , Rasmus Vendler Toft-Kehler
    •  & Dan I. Andersson

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