Review
Nature Reviews Molecular Cell Biology 7, 276-285 (April 2006) | doi:10.1038/nrm1893
Sperm guidance in mammals — an unpaved road to the egg
Michael Eisenbach1 & Laura C. Giojalas2 About the authors
Abstract
Contrary to the prevalent view, there seems to be no competition in the mammalian female genital tract among large numbers of sperm cells that are racing towards the egg. Instead, small numbers of the ejaculated sperm cells enter the Fallopian tube, and these few must be guided to make the remaining long, obstructed way to the egg. Here, we review the mechanisms by which mammalian sperm cells are guided to the egg.
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Author affiliations
- Department of Biological Chemistry, the Weizmann Institute of Science, 76100 Rehovot, Israel.
- Center for Cell and Molecular Biology, Faculty of Sciences, National University of Córdoba, Avenue Vélez Sársfield 1601, 5000, Córdoba, Argentina.
Correspondence to: Michael Eisenbach1 Email: m.eisenbach@weizmann.ac.il
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