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Studies of mechanobiology lie at the interface of various scientific disciplines from biology to physics. Ulrich Schwarz discusses the importance of technological advances, quantification and modelling for the progress in understanding the role of forces in biology.
Novoa, Mason and Mattick propose to use phage display technology and direct sequencing through nanopores to facilitate systematic interrogation of RNA modifications.
Job Dekker asserts that cases in which data from microscopy- and 3C-based methods appear discordant about genome organization will provide opportunities to improve our models of chromatin folding.
Tomas Lindahl presents a case for keeping DNA in the organic solvent glycol, in which it keeps its activity and is better protected from contamination and, potentially, radiation.
